Symbol Name ID |
Map3k7
mitogen-activated protein kinase kinase kinase 7 MGI:1346877 |
Category | GO ID | Classification Term | Evidence | Reference | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Molecular Function | GO:0005524 | ATP binding | ISO | J:155856 | |||||||||
Molecular Function | GO:0042802 | identical protein binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0016301 | kinase activity | IEA | J:60000 | |||||||||
Molecular Function | GO:1990450 | linear polyubiquitin binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0000287 | magnesium ion binding | IEA | J:72247 | |||||||||
Molecular Function | GO:0004707 | MAP kinase activity | ISO | J:164563 | |||||||||
Molecular Function | GO:0004708 | MAP kinase kinase activity | IDA | J:80766 | |||||||||
Molecular Function | GO:0004709 | MAP kinase kinase kinase activity | ISO | J:164563 | |||||||||
Molecular Function | GO:0004709 | MAP kinase kinase kinase activity | ISO | J:155856 | |||||||||
Molecular Function | GO:0004709 | MAP kinase kinase kinase activity | IBA | J:265628 | |||||||||
Molecular Function | GO:0008349 | MAP kinase kinase kinase kinase activity | IMP | J:163789 | |||||||||
Molecular Function | GO:0046872 | metal ion binding | IEA | J:60000 | |||||||||
Molecular Function | GO:0000166 | nucleotide binding | IEA | J:60000 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:236517 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:150837 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:279494 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:148055 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:201312 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:206842 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:120934 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:259108 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:245318 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:179005 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:166091 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:84524 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:208236 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:84524 | |||||||||
Molecular Function | GO:0004672 | protein kinase activity | ISO | J:164563 | |||||||||
Molecular Function | GO:0004674 | protein serine/threonine kinase activity | ISO | J:164563 | |||||||||
Molecular Function | GO:0004674 | protein serine/threonine kinase activity | IDA | J:259108 | |||||||||
Molecular Function | GO:0004674 | protein serine/threonine kinase activity | TAS | Reactome:R-MMU-209329 | |||||||||
Molecular Function | GO:0030971 | receptor tyrosine kinase binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0030971 | receptor tyrosine kinase binding | IPI | J:259108 | |||||||||
Molecular Function | GO:0097110 | scaffold protein binding | ISO | J:205449 | |||||||||
Molecular Function | GO:0016740 | transferase activity | IEA | J:60000 | |||||||||
Cellular Component | GO:0140672 | ATAC complex | ISO | J:164563 | |||||||||
Cellular Component | GO:0005737 | cytoplasm | ISO | J:164563 | |||||||||
Cellular Component | GO:0005829 | cytosol | ISO | J:164563 | |||||||||
Cellular Component | GO:0005829 | cytosol | TAS | Reactome:R-MMU-209329 | |||||||||
Cellular Component | GO:0008385 | IkappaB kinase complex | ISO | J:164563 | |||||||||
Cellular Component | GO:0016020 | membrane | IEA | J:60000 | |||||||||
Cellular Component | GO:0005886 | plasma membrane | ISO | J:164563 | |||||||||
Cellular Component | GO:0014069 | postsynaptic density | IDA | J:187362 | |||||||||
Biological Process | GO:0007250 | activation of NF-kappaB-inducing kinase activity | ISO | J:164563 | |||||||||
Biological Process | GO:0001525 | angiogenesis | IMP | J:107401 | |||||||||
Biological Process | GO:0043276 | anoikis | IMP | J:238448 | |||||||||
Biological Process | GO:0006915 | apoptotic process | IEA | J:60000 | |||||||||
Biological Process | GO:0097190 | apoptotic signaling pathway | IGI | J:102721 | |||||||||
Biological Process | GO:0097190 | apoptotic signaling pathway | IMP | J:102721 | |||||||||
Biological Process | GO:0060348 | bone development | IMP | J:163789 | |||||||||
Biological Process | GO:0043966 | histone H3 acetylation | ISO | J:164563 | |||||||||
Biological Process | GO:0007249 | I-kappaB kinase/NF-kappaB signaling | ISO | J:164563 | |||||||||
Biological Process | GO:0007249 | I-kappaB kinase/NF-kappaB signaling | IGI | J:102721 | |||||||||
Biological Process | GO:0007249 | I-kappaB kinase/NF-kappaB signaling | IGI | J:102721 | |||||||||
Biological Process | GO:0007249 | I-kappaB kinase/NF-kappaB signaling | IGI | J:102721 | |||||||||
Biological Process | GO:0007252 | I-kappaB phosphorylation | ISO | J:164563 | |||||||||
Biological Process | GO:0007252 | I-kappaB phosphorylation | IGI | J:102721 | |||||||||
Biological Process | GO:0007252 | I-kappaB phosphorylation | IGI | J:102721 | |||||||||
Biological Process | GO:0038173 | interleukin-17A-mediated signaling pathway | ISO | J:164563 | |||||||||
Biological Process | GO:0007254 | JNK cascade | IDA | J:262344 | |||||||||
Biological Process | GO:0007254 | JNK cascade | ISO | J:164563 | |||||||||
Biological Process | GO:0007254 | JNK cascade | IBA | J:265628 | |||||||||
Biological Process | GO:0007254 | JNK cascade | IGI | J:102721 | |||||||||
Biological Process | GO:0007254 | JNK cascade | IGI | J:102721 | |||||||||
Biological Process | GO:0007254 | JNK cascade | IGI | J:102721 | |||||||||
Biological Process | GO:0000165 | MAPK cascade | ISO | J:164563 | |||||||||
Biological Process | GO:0000165 | MAPK cascade | ISO | J:155856 | |||||||||
Biological Process | GO:0000165 | MAPK cascade | IMP | J:163789 | |||||||||
Biological Process | GO:0000165 | MAPK cascade | IDA | J:84524 | |||||||||
Biological Process | GO:2001234 | negative regulation of apoptotic signaling pathway | IGI | J:102721 | |||||||||
Biological Process | GO:2001234 | negative regulation of apoptotic signaling pathway | IMP | J:102721 | |||||||||
Biological Process | GO:0060546 | negative regulation of necroptotic process | IMP | J:182381 | |||||||||
Biological Process | GO:2000378 | negative regulation of reactive oxygen species metabolic process | IMP | J:182381 | |||||||||
Biological Process | GO:1902443 | negative regulation of ripoptosome assembly involved in necroptotic process | IGI | J:182381 | |||||||||
Biological Process | GO:1902443 | negative regulation of ripoptosome assembly involved in necroptotic process | IGI | J:182381 | |||||||||
Biological Process | GO:0001841 | neural tube formation | IMP | J:102721 | |||||||||
Biological Process | GO:0001649 | osteoblast differentiation | IMP | J:163789 | |||||||||
Biological Process | GO:0018107 | peptidyl-threonine phosphorylation | IDA | J:259108 | |||||||||
Biological Process | GO:0016310 | phosphorylation | IEA | J:60000 | |||||||||
Biological Process | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | ISO | J:155856 | |||||||||
Biological Process | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | ISO | J:164563 | |||||||||
Biological Process | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | IBA | J:265628 | |||||||||
Biological Process | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | IGI | J:102721 | |||||||||
Biological Process | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | IGI | J:102721 | |||||||||
Biological Process | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | IGI | J:102721 | |||||||||
Biological Process | GO:0032743 | positive regulation of interleukin-2 production | ISO | J:164563 | |||||||||
Biological Process | GO:0046330 | positive regulation of JNK cascade | IGI | J:102721 | |||||||||
Biological Process | GO:0046330 | positive regulation of JNK cascade | IGI | J:102721 | |||||||||
Biological Process | GO:0046330 | positive regulation of JNK cascade | IGI | J:102721 | |||||||||
Biological Process | GO:0043507 | positive regulation of JUN kinase activity | ISO | J:164563 | |||||||||
Biological Process | GO:0016239 | positive regulation of macroautophagy | IMP | J:238448 | |||||||||
Biological Process | GO:0043410 | positive regulation of MAPK cascade | ISO | J:155856 | |||||||||
Biological Process | GO:0002726 | positive regulation of T cell cytokine production | ISO | J:164563 | |||||||||
Biological Process | GO:0006468 | protein phosphorylation | ISO | J:155856 | |||||||||
Biological Process | GO:0006468 | protein phosphorylation | IDA | J:251915 | |||||||||
Biological Process | GO:0006468 | protein phosphorylation | IDA | J:80766 | |||||||||
Biological Process | GO:2000377 | regulation of reactive oxygen species metabolic process | IMP | J:182381 | |||||||||
Biological Process | GO:0007165 | signal transduction | IEA | J:72247 | |||||||||
Biological Process | GO:0051403 | stress-activated MAPK cascade | ISO | J:164563 | |||||||||
Biological Process | GO:0007179 | transforming growth factor beta receptor signaling pathway | IMP | J:102271 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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