GO Annotations Graph

• Symbol: Abcg2
• Name: ATP binding cassette subfamily G member 2 (Junior blood group)
• ID: MGI:1347061

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0140359	ABC-type transporter activity	IEA	J:72247
Molecular Function	GO:0008559	ABC-type xenobiotic transporter activity	ISO	J:164563
Molecular Function	GO:0042887	amide transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0042626	ATPase-coupled transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0042626	ATPase-coupled transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0015225	biotin transmembrane transporter activity	IMP	J:118277
Molecular Function	GO:0008092	cytoskeletal protein binding	ISO	J:155856
Molecular Function	GO:0015562	efflux transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015562	efflux transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015562	efflux transmembrane transporter activity	IMP	J:118277
Molecular Function	GO:0015562	efflux transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0008514	organic anion transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0032217	riboflavin transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0032217	riboflavin transmembrane transporter activity	IMP	J:118277
Molecular Function	GO:0032217	riboflavin transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0015143	urate transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0042910	xenobiotic transmembrane transporter activity	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:80519
Cellular Component	GO:0031526	brush border membrane	ISO	J:164563
Cellular Component	GO:0098591	external side of apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0045121	membrane raft	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-2161533
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0015878	biotin transport	IMP	J:118277
Biological Process	GO:1990748	cellular detoxification	ISO	J:164563
Biological Process	GO:0060136	embryonic process involved in female pregnancy	ISO	J:155856
Biological Process	GO:0140115	export across plasma membrane	ISO	J:155856
Biological Process	GO:0019389	glucuronoside metabolic process	ISO	J:155856
Biological Process	GO:0006869	lipid transport	IEA	J:60000
Biological Process	GO:1904479	negative regulation of intestinal absorption	ISO	J:155856
Biological Process	GO:0015711	organic anion transport	ISO	J:155856
Biological Process	GO:0065003	protein-containing complex assembly	ISO	J:155856
Biological Process	GO:0097744	renal urate salt excretion	ISO	J:164563
Biological Process	GO:0032218	riboflavin transport	ISO	J:164563
Biological Process	GO:0032218	riboflavin transport	IMP	J:118277
Biological Process	GO:0070633	transepithelial transport	ISO	J:164563
Biological Process	GO:0055085	transmembrane transport	ISO	J:155856
Biological Process	GO:0055085	transmembrane transport	ISO	J:164563
Biological Process	GO:0055085	transmembrane transport	IBA	J:265628
Biological Process	GO:0046415	urate metabolic process	ISO	J:164563
Biological Process	GO:0015747	urate transport	ISO	J:155856
Biological Process	GO:1990961	xenobiotic detoxification by transmembrane export across the plasma membrane	ISO	J:155856
Biological Process	GO:1990962	xenobiotic transport across blood-brain barrier	ISO	J:164563