GO Annotations Graph

• Symbol: Creb3l1
• Name: cAMP responsive element binding protein 3-like 1
• ID: MGI:1347062

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0035497	cAMP response element binding	IDA	J:158242
Molecular Function	GO:0035497	cAMP response element binding	IBA	J:265628
Molecular Function	GO:0003682	chromatin binding	IDA	J:158242
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:158242
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISS	J:57177
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0046332	SMAD binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:217998
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:155856
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-8874364
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-8874373
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:217998
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:158242
Cellular Component	GO:0005789	endoplasmic reticulum membrane	TAS	J:217998
Cellular Component	GO:0005789	endoplasmic reticulum membrane	TAS	Reactome:R-MMU-8874370
Cellular Component	GO:0000139	Golgi membrane	TAS	Reactome:R-MMU-8874364
Cellular Component	GO:0000139	Golgi membrane	TAS	Reactome:R-MMU-8874370
Cellular Component	GO:0000139	Golgi membrane	TAS	Reactome:R-MMU-8874394
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-8874373
Cellular Component	GO:0005634	nucleus	IDA	J:217998
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:158242
Biological Process	GO:0006351	DNA-templated transcription	IDA	J:158242
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	IDA	J:158242
Biological Process	GO:0070278	extracellular matrix constituent secretion	IDA	J:158242
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	ISO	J:155856
Biological Process	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	IDA	J:217998
Biological Process	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:164563
Biological Process	GO:1903671	negative regulation of sprouting angiogenesis	ISO	J:164563
Biological Process	GO:0001649	osteoblast differentiation	IMP	J:158242
Biological Process	GO:0032967	positive regulation of collagen biosynthetic process	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:158242
Biological Process	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	ISO	J:155856
Biological Process	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	IDA	J:217998
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0030278	regulation of ossification	IMP	J:158242
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006986	response to unfolded protein	IEA	J:60000