GO Annotations Graph

• Symbol: Homer2
• Name: homer scaffolding protein 2
• ID: MGI:1347354

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IDA	J:57662
Molecular Function	GO:0035256	G protein-coupled glutamate receptor binding	ISO	J:155856
Molecular Function	GO:0035256	G protein-coupled glutamate receptor binding	IBA	J:265628
Molecular Function	GO:0035254	glutamate receptor binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:50718
Molecular Function	GO:0005515	protein binding	IPI	J:57662
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0030160	synaptic receptor adaptor activity	IDA	J:57662
Cellular Component	GO:0045177	apical part of cell	IDA	J:95213
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IMP	J:57662
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0030425	dendrite	IBA	J:265628
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:210337
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:210337
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:210337
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:210337
Cellular Component	GO:0043229	intracellular organelle	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0014069	postsynaptic density	IBA	J:265628
Cellular Component	GO:0014069	postsynaptic density	IDA	J:210337
Cellular Component	GO:0014069	postsynaptic density	IDA	J:210337
Cellular Component	GO:0014069	postsynaptic density	IDA	J:210337
Cellular Component	GO:0014069	postsynaptic density	IDA	J:210337
Cellular Component	GO:0032426	stereocilium tip	IDA	J:224710
Cellular Component	GO:0045202	synapse	IEA	J:60000
Biological Process	GO:0048148	behavioral response to cocaine	IMP	J:96554
Biological Process	GO:0035584	calcium-mediated signaling using intracellular calcium source	IMP	J:95213
Biological Process	GO:0007216	G protein-coupled glutamate receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007216	G protein-coupled glutamate receptor signaling pathway	TAS	J:57662
Biological Process	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade	ISO	J:164563
Biological Process	GO:0032703	negative regulation of interleukin-2 production	ISO	J:164563
Biological Process	GO:0008277	regulation of G protein-coupled receptor signaling pathway	IDA	J:95213
Biological Process	GO:2001256	regulation of store-operated calcium entry	IBA	J:265628
Biological Process	GO:0007605	sensory perception of sound	ISO	J:164563
Biological Process	GO:0007605	sensory perception of sound	IMP	J:224710