GO Annotations Graph

• Symbol: Foxa1
• Name: forkhead box A1
• ID: MGI:1347472

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:188795
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:94197
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:155856
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:73065
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:53312
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:53312
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:155856
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:16244
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:187177
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0008134	transcription factor binding	ISO	J:73065
Cellular Component	GO:0001650	fibrillar center	ISO	J:164563
Cellular Component	GO:0005902	microvillus	IDA	J:194289
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:101172
Cellular Component	GO:0005634	nucleus	IDA	J:16244
Cellular Component	GO:0005634	nucleus	IDA	J:94057
Cellular Component	GO:0005634	nucleus	IDA	J:94921
Cellular Component	GO:0005634	nucleus	IDA	J:101172
Cellular Component	GO:0005634	nucleus	IDA	J:101172
Cellular Component	GO:0005634	nucleus	IDA	J:94057
Cellular Component	GO:0005634	nucleus	IDA	J:94921
Cellular Component	GO:0005634	nucleus	IDA	J:94057
Cellular Component	GO:0005634	nucleus	IDA	J:94057
Cellular Component	GO:0005634	nucleus	IDA	J:94057
Biological Process	GO:0061144	alveolar secondary septum development	IMP	J:104973
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	IGI	J:195910
Biological Process	GO:0009653	anatomical structure morphogenesis	IBA	J:265628
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0006338	chromatin remodeling	IDA	J:161021
Biological Process	GO:0061448	connective tissue development	IGI	J:195910
Biological Process	GO:0071542	dopaminergic neuron differentiation	IMP	J:124122
Biological Process	GO:0071542	dopaminergic neuron differentiation	IGI	J:124122
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	IGI	J:195910
Biological Process	GO:0060743	epithelial cell maturation involved in prostate gland development	IMP	J:101172
Biological Process	GO:0060743	epithelial cell maturation involved in prostate gland development	IMP	J:101172
Biological Process	GO:0060441	epithelial tube branching involved in lung morphogenesis	IGI	J:98750
Biological Process	GO:0060738	epithelial-mesenchymal signaling involved in prostate gland development	IGI	J:101172
Biological Process	GO:0042593	glucose homeostasis	IMP	J:53312
Biological Process	GO:0042445	hormone metabolic process	IMP	J:53312
Biological Process	GO:0030324	lung development	IGI	J:98750
Biological Process	GO:0060487	lung epithelial cell differentiation	IGI	J:98750
Biological Process	GO:0060425	lung morphogenesis	IMP	J:104973
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0010719	negative regulation of epithelial to mesenchymal transition	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:73065
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:118897
Biological Process	GO:0030182	neuron differentiation	IGI	J:124122
Biological Process	GO:0030182	neuron differentiation	IMP	J:124122
Biological Process	GO:0048665	neuron fate specification	IGI	J:124122
Biological Process	GO:0007219	Notch signaling pathway	IDA	J:218171
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:1904340	positive regulation of dopaminergic neuron differentiation	IMP	J:124122
Biological Process	GO:1904340	positive regulation of dopaminergic neuron differentiation	IGI	J:124122
Biological Process	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death	ISO	J:155856
Biological Process	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway	ISO	J:164563
Biological Process	GO:0045931	positive regulation of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	IGI	J:195910
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:96456
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:53312
Biological Process	GO:0060740	prostate gland epithelium morphogenesis	IMP	J:101172
Biological Process	GO:0060741	prostate gland stromal morphogenesis	IMP	J:101172
Biological Process	GO:0051726	regulation of cell cycle	IMP	J:187177
Biological Process	GO:0051726	regulation of cell cycle	IDA	J:187177
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0010468	regulation of gene expression	IGI	J:124122
Biological Process	GO:0010468	regulation of gene expression	IGI	J:124122
Biological Process	GO:0010468	regulation of gene expression	IGI	J:124122
Biological Process	GO:0010468	regulation of gene expression	IGI	J:124122
Biological Process	GO:0010468	regulation of gene expression	IGI	J:124122
Biological Process	GO:0010468	regulation of gene expression	IGI	J:124122
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IMP	J:104973
Biological Process	GO:1902691	respiratory basal cell differentiation	IMP	J:104973
Biological Process	GO:0032355	response to estradiol	ISO	J:164563
Biological Process	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	IMP	J:101172
Biological Process	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	IMP	J:101172
Biological Process	GO:0007224	smoothened signaling pathway	IGI	J:195910
Biological Process	GO:0035239	tube morphogenesis	IMP	J:101172