Foxa2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Foxa2
forkhead box A2
MGI:1347476

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:188795
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:155856
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:185583
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:155856
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:80826
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:77089
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:188772
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:64004
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:88815
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0003690	double-stranded DNA binding	IGI	J:216917
Molecular Function	GO:0019900	kinase binding	ISO	J:155856
Molecular Function	GO:0003676	nucleic acid binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:161781
Molecular Function	GO:0019904	protein domain specific binding	IEA	J:72247
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:111670
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:80826
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:94197
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:100426
Molecular Function	GO:0016251	RNA polymerase II general transcription initiation factor activity	TAS	J:226614
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:88815
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:187177
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:77089
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0046332	SMAD binding	ISO	J:155856
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0008134	transcription factor binding	IEA	J:72247
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9796221
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:35560
Cellular Component	GO:0005634	nucleus	IDA	J:94057
Cellular Component	GO:0005634	nucleus	IDA	J:35560
Cellular Component	GO:0005634	nucleus	IDA	J:195910
Cellular Component	GO:0005634	nucleus	IDA	J:35560
Cellular Component	GO:0005634	nucleus	IDA	J:35560
Cellular Component	GO:0005634	nucleus	IDA	J:94057
Cellular Component	GO:0005634	nucleus	IDA	J:119866
Cellular Component	GO:0005634	nucleus	IDA	J:35560
Cellular Component	GO:0005634	nucleus	IDA	J:35560
Cellular Component	GO:0005634	nucleus	IDA	J:94057
Cellular Component	GO:0005634	nucleus	IDA	J:35560
Cellular Component	GO:0005634	nucleus	IDA	J:195910
Cellular Component	GO:0005634	nucleus	IDA	J:94057
Cellular Component	GO:0005634	nucleus	IDA	J:35560
Cellular Component	GO:0005634	nucleus	IDA	J:80826
Cellular Component	GO:0005634	nucleus	IDA	J:35560
Cellular Component	GO:0005634	nucleus	IDA	J:35560
Cellular Component	GO:0005634	nucleus	IDA	J:35560
Cellular Component	GO:0005634	nucleus	IDA	J:35560
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:226614
Biological Process	GO:0008344	adult locomotory behavior	IMP	J:130846
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	IGI	J:195910
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	IGI	J:53656
Biological Process	GO:0009653	anatomical structure morphogenesis	IBA	J:265628
Biological Process	GO:0009653	anatomical structure morphogenesis	IGI	J:41809
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:53656
Biological Process	GO:0048468	cell development	IMP	J:96332
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0030154	cell differentiation	TAS	J:226614
Biological Process	GO:0021533	cell differentiation in hindbrain	IMP	J:128441
Biological Process	GO:0021533	cell differentiation in hindbrain	IGI	J:128441
Biological Process	GO:0021533	cell differentiation in hindbrain	IMP	J:128441
Biological Process	GO:0021533	cell differentiation in hindbrain	IGI	J:128441
Biological Process	GO:0001708	cell fate specification	IDA	J:130846
Biological Process	GO:0071276	cellular response to cadmium ion	IDA	J:297615
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0061448	connective tissue development	IGI	J:195910
Biological Process	GO:0006351	DNA-templated transcription	IDA	J:88815
Biological Process	GO:0071542	dopaminergic neuron differentiation	ISO	J:164563
Biological Process	GO:0071542	dopaminergic neuron differentiation	IMP	J:130846
Biological Process	GO:0071542	dopaminergic neuron differentiation	IGI	J:124122
Biological Process	GO:0071542	dopaminergic neuron differentiation	IMP	J:124122
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	IDA	J:138713
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	IGI	J:195910
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	IGI	J:41809
Biological Process	GO:0009953	dorsal/ventral pattern formation	IGI	J:53656
Biological Process	GO:0001705	ectoderm formation	IGI	J:53656
Biological Process	GO:0031018	endocrine pancreas development	ISO	J:164563
Biological Process	GO:0031018	endocrine pancreas development	IMP	J:96332
Biological Process	GO:0060441	epithelial tube branching involved in lung morphogenesis	IGI	J:98750
Biological Process	GO:0010467	gene expression	IMP	J:262053
Biological Process	GO:0010255	glucose mediated signaling pathway	IDA	J:175106
Biological Process	GO:0001701	in utero embryonic development	IMP	J:39656
Biological Process	GO:0030324	lung development	IGI	J:98750
Biological Process	GO:0060487	lung epithelial cell differentiation	IGI	J:98750
Biological Process	GO:0048382	mesendoderm development	IMP	J:226614
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0010719	negative regulation of epithelial to mesenchymal transition	ISO	J:164563
Biological Process	GO:0033132	negative regulation of glucokinase activity	IDA	J:175106
Biological Process	GO:0045665	negative regulation of neuron differentiation	IGI	J:128441
Biological Process	GO:0061987	negative regulation of transcription from RNA polymerase II promoter by glucose	IDA	J:175106
Biological Process	GO:0030182	neuron differentiation	IGI	J:128441
Biological Process	GO:0030182	neuron differentiation	IGI	J:124122
Biological Process	GO:0030182	neuron differentiation	IMP	J:128441
Biological Process	GO:0030182	neuron differentiation	IGI	J:128441
Biological Process	GO:0030182	neuron differentiation	IMP	J:128441
Biological Process	GO:0030182	neuron differentiation	IMP	J:124122
Biological Process	GO:0030182	neuron differentiation	IGI	J:128441
Biological Process	GO:0030182	neuron differentiation	IGI	J:128441
Biological Process	GO:0030182	neuron differentiation	IGI	J:128441
Biological Process	GO:0048665	neuron fate specification	IGI	J:124122
Biological Process	GO:0048665	neuron fate specification	IMP	J:128441
Biological Process	GO:0007219	Notch signaling pathway	IDA	J:218171
Biological Process	GO:0007389	pattern specification process	IGI	J:53656
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:74124
Biological Process	GO:1904340	positive regulation of dopaminergic neuron differentiation	IGI	J:124122
Biological Process	GO:1904340	positive regulation of dopaminergic neuron differentiation	IMP	J:124122
Biological Process	GO:0040019	positive regulation of embryonic development	IMP	J:74124
Biological Process	GO:2000543	positive regulation of gastrulation	IMP	J:74124
Biological Process	GO:0045666	positive regulation of neuron differentiation	IGI	J:128441
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	IGI	J:195910
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:64004
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:39656
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:77089
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:185583
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:185583
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:39656
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:96456
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:185583
Biological Process	GO:0045945	positive regulation of transcription by RNA polymerase III	IMP	J:161022
Biological Process	GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose	IDA	J:175106
Biological Process	GO:0090009	primitive streak formation	IMP	J:74124
Biological Process	GO:0030193	regulation of blood coagulation	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:80826
Biological Process	GO:0010468	regulation of gene expression	IGI	J:124122
Biological Process	GO:0010468	regulation of gene expression	IGI	J:124122
Biological Process	GO:0010468	regulation of gene expression	IGI	J:124122
Biological Process	GO:0010468	regulation of gene expression	IGI	J:124122
Biological Process	GO:0010468	regulation of gene expression	IGI	J:124122
Biological Process	GO:0010468	regulation of gene expression	IGI	J:124122
Biological Process	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	IDA	J:175106
Biological Process	GO:0019216	regulation of lipid metabolic process	IDA	J:187177
Biological Process	GO:0019216	regulation of lipid metabolic process	IMP	J:187177
Biological Process	GO:0019218	regulation of steroid metabolic process	IDA	J:187177
Biological Process	GO:0019218	regulation of steroid metabolic process	IMP	J:187177
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:88815
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0070741	response to interleukin-6	TAS	J:161022
Biological Process	GO:0023019	signal transduction involved in regulation of gene expression	IDA	J:155850
Biological Process	GO:0007224	smoothened signaling pathway	IGI	J:195910
Biological Process	GO:0032525	somite rostral/caudal axis specification	IMP	J:74124
Biological Process	GO:0006366	transcription by RNA polymerase II	IDA	J:64004

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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