Foxc2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Foxc2
forkhead box C2
MGI:1347481

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031490	chromatin DNA binding	ISS	J:40156
Molecular Function	GO:0031490	chromatin DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	ISO	J:155856
Molecular Function	GO:0003677	DNA binding	IDA	J:33942
Molecular Function	GO:0001216	DNA-binding transcription activator activity	IDA	J:40156
Molecular Function	GO:0001216	DNA-binding transcription activator activity	ISO	J:164563
Molecular Function	GO:0001216	DNA-binding transcription activator activity	ISS	J:40156
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IMP	J:131323
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:140365
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IGI	J:119144
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:1990841	promoter-specific chromatin binding	IDA	J:131323
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	ISS	J:40156
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:140365
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0009653	anatomical structure morphogenesis	IBA	J:265628
Biological Process	GO:0003275	apoptotic process involved in outflow tract morphogenesis	IGI	J:119303
Biological Process	GO:0048844	artery morphogenesis	IMP	J:55316
Biological Process	GO:0048844	artery morphogenesis	IMP	J:57677
Biological Process	GO:0001568	blood vessel development	IGI	J:119144
Biological Process	GO:0097746	blood vessel diameter maintenance	IGI	J:119144
Biological Process	GO:0001974	blood vessel remodeling	IGI	J:119144
Biological Process	GO:0001974	blood vessel remodeling	IGI	J:71693
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	IGI	J:102130
Biological Process	GO:0043010	camera-type eye development	IMP	J:61775
Biological Process	GO:0060038	cardiac muscle cell proliferation	IGI	J:119303
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0008283	cell population proliferation	IMP	J:39636
Biological Process	GO:0008283	cell population proliferation	IMP	J:55575
Biological Process	GO:0030199	collagen fibril organization	IMP	J:61775
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	IMP	J:39636
Biological Process	GO:0035050	embryonic heart tube development	IGI	J:119144
Biological Process	GO:0035050	embryonic heart tube development	IGI	J:119144
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	IMP	J:55316
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	IMP	J:55316
Biological Process	GO:0072011	glomerular endothelium development	IMP	J:106710
Biological Process	GO:0072144	glomerular mesangial cell development	IMP	J:106710
Biological Process	GO:0007507	heart development	ISO	J:164563
Biological Process	GO:0007507	heart development	IGI	J:102130
Biological Process	GO:0007507	heart development	IGI	J:102130
Biological Process	GO:0007507	heart development	IGI	J:119303
Biological Process	GO:0007507	heart development	IMP	J:57677
Biological Process	GO:0007507	heart development	IGI	J:102130
Biological Process	GO:0003007	heart morphogenesis	IGI	J:119303
Biological Process	GO:0008286	insulin receptor signaling pathway	ISS	J:40156
Biological Process	GO:0008286	insulin receptor signaling pathway	ISO	J:164563
Biological Process	GO:0001822	kidney development	IMP	J:60834
Biological Process	GO:0001945	lymph vessel development	IGI	J:119144
Biological Process	GO:0001946	lymphangiogenesis	ISO	J:164563
Biological Process	GO:0001946	lymphangiogenesis	ISS	J:40156
Biological Process	GO:0001656	metanephros development	IMP	J:106710
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:1902257	negative regulation of apoptotic process involved in outflow tract morphogenesis	IGI	J:119303
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	ISO	J:164563
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	ISS	J:94144
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:140365
Biological Process	GO:0014032	neural crest cell development	IGI	J:119303
Biological Process	GO:0014032	neural crest cell development	IGI	J:119303
Biological Process	GO:0014032	neural crest cell development	IGI	J:119303
Biological Process	GO:0007219	Notch signaling pathway	IGI	J:71693
Biological Process	GO:0001503	ossification	IMP	J:39636
Biological Process	GO:0048341	paraxial mesoderm formation	IGI	J:71693
Biological Process	GO:0048343	paraxial mesodermal cell fate commitment	IMP	J:39636
Biological Process	GO:0072112	podocyte differentiation	IMP	J:106710
Biological Process	GO:0033630	positive regulation of cell adhesion mediated by integrin	IDA	J:140365
Biological Process	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	IDA	J:140365
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISS	J:40156
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:40156
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0010595	positive regulation of endothelial cell migration	IDA	J:140365
Biological Process	GO:0033625	positive regulation of integrin activation	IC	J:140365
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:140365
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:131323
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:119144
Biological Process	GO:0035470	positive regulation of vascular wound healing	IDA	J:140365
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0046620	regulation of organ growth	IGI	J:119303
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0009725	response to hormone	ISS	J:40156
Biological Process	GO:0009725	response to hormone	ISO	J:164563
Biological Process	GO:0001501	skeletal system development	IMP	J:55575
Biological Process	GO:0001501	skeletal system development	IGI	J:55575
Biological Process	GO:0001756	somitogenesis	IGI	J:71693
Biological Process	GO:0001657	ureteric bud development	IMP	J:60834
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	IGI	J:119144
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	IGI	J:119144
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	IGI	J:119144
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	IGI	J:119144
Biological Process	GO:0055010	ventricular cardiac muscle tissue morphogenesis	IGI	J:119303

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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