Ror2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Ror2
receptor tyrosine kinase-like orphan receptor 2
MGI:1347521

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005109	frizzled binding	IPI	J:89972
Molecular Function	GO:0005109	frizzled binding	IPI	J:140886
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0031435	mitogen-activated protein kinase kinase kinase binding	ISO	J:164563
Molecular Function	GO:0031435	mitogen-activated protein kinase kinase kinase binding	IPI	J:259108
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:259108
Molecular Function	GO:0005515	protein binding	IPI	J:192848
Molecular Function	GO:0005515	protein binding	IPI	J:89972
Molecular Function	GO:0005515	protein binding	IPI	J:89972
Molecular Function	GO:0005515	protein binding	IPI	J:140886
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	IBA	J:265628
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	TAS	J:57217
Molecular Function	GO:0017147	Wnt-protein binding	ISO	J:164563
Molecular Function	GO:0017147	Wnt-protein binding	IBA	J:265628
Molecular Function	GO:0017147	Wnt-protein binding	IPI	J:140886
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005874	microtubule	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-4551566
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-4551572
Cellular Component	GO:0005886	plasma membrane	ISS	J:57217
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Cellular Component	GO:0043235	receptor complex	IBA	J:265628
Biological Process	GO:0014002	astrocyte development	ISO	J:155856
Biological Process	GO:0030509	BMP signaling pathway	IMP	J:163602
Biological Process	GO:0001502	cartilage condensation	IMP	J:88955
Biological Process	GO:0001502	cartilage condensation	IMP	J:88955
Biological Process	GO:0001502	cartilage condensation	IMP	J:88955
Biological Process	GO:0001502	cartilage condensation	IMP	J:88955
Biological Process	GO:0045165	cell fate commitment	IMP	J:163602
Biological Process	GO:0002062	chondrocyte differentiation	IMP	J:88955
Biological Process	GO:0042733	embryonic digit morphogenesis	IGI	J:163602
Biological Process	GO:0042733	embryonic digit morphogenesis	IMP	J:163602
Biological Process	GO:0042733	embryonic digit morphogenesis	IMP	J:163602
Biological Process	GO:0030538	embryonic genitalia morphogenesis	IMP	J:88955
Biological Process	GO:0042472	inner ear morphogenesis	IMP	J:140886
Biological Process	GO:0007254	JNK cascade	IDA	J:89972
Biological Process	GO:1905517	macrophage migration	ISO	J:155856
Biological Process	GO:0050804	modulation of chemical synaptic transmission	ISO	J:155856
Biological Process	GO:0007275	multicellular organism development	IBA	J:265628
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IGI	J:107727
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	IDA	J:164777
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:164777
Biological Process	GO:0043507	positive regulation of JUN kinase activity	ISO	J:155856
Biological Process	GO:0033674	positive regulation of kinase activity	IBA	J:265628
Biological Process	GO:0045651	positive regulation of macrophage differentiation	ISO	J:155856
Biological Process	GO:0010976	positive regulation of neuron projection development	IBA	J:265628
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	IBA	J:265628
Biological Process	GO:1900020	positive regulation of protein kinase C activity	ISO	J:155856
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	ISO	J:155856
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:0060828	regulation of canonical Wnt signaling pathway	IMP	J:163602
Biological Process	GO:0099175	regulation of postsynapse organization	ISO	J:155856
Biological Process	GO:0150045	regulation of synaptic signaling by nitric oxide	ISO	J:155856
Biological Process	GO:0007165	signal transduction	ISO	J:164563
Biological Process	GO:0001501	skeletal system development	IMP	J:60754
Biological Process	GO:0060395	SMAD protein signal transduction	IMP	J:163602
Biological Process	GO:0060395	SMAD protein signal transduction	IMP	J:163602
Biological Process	GO:0007224	smoothened signaling pathway	IMP	J:163602
Biological Process	GO:0001756	somitogenesis	IMP	J:88955
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IBA	J:265628
Biological Process	GO:0016055	Wnt signaling pathway	IEA	J:60000
Biological Process	GO:0007223	Wnt signaling pathway, calcium modulating pathway	IPI	J:89972
Biological Process	GO:0007223	Wnt signaling pathway, calcium modulating pathway	IPI	J:89972
Biological Process	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	IMP	J:140886

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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