GO Annotations Graph

• Symbol: Dysf
• Name: dysferlin
• ID: MGI:1349385

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043014	alpha-tubulin binding	IPI	J:160150
Molecular Function	GO:0043014	alpha-tubulin binding	IDA	J:182257
Molecular Function	GO:0043014	alpha-tubulin binding	IDA	J:160150
Molecular Function	GO:0043014	alpha-tubulin binding	IPI	J:160150
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	ISO	J:164563
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008017	microtubule binding	IDA	J:160150
Molecular Function	GO:0005543	phospholipid binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:215951
Molecular Function	GO:0005515	protein binding	IPI	J:205677
Molecular Function	GO:0005515	protein binding	IPI	J:87169
Molecular Function	GO:0005515	protein binding	IPI	J:160150
Molecular Function	GO:0005515	protein binding	IPI	J:160150
Molecular Function	GO:0005515	protein binding	IPI	J:186896
Molecular Function	GO:0005515	protein binding	IPI	J:87169
Molecular Function	GO:0005515	protein binding	IPI	J:150684
Molecular Function	GO:0005515	protein binding	IPI	J:150684
Molecular Function	GO:0005515	protein binding	IPI	J:160150
Molecular Function	GO:0005515	protein binding	IPI	J:182257
Molecular Function	GO:0005515	protein binding	IPI	J:160150
Molecular Function	GO:0005515	protein binding	IPI	J:160150
Molecular Function	GO:0005515	protein binding	IPI	J:160150
Cellular Component	GO:0034451	centriolar satellite	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:182257
Cellular Component	GO:0031410	cytoplasmic vesicle	IDA	J:83126
Cellular Component	GO:0031410	cytoplasmic vesicle	IBA	J:265628
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	TAS	Reactome:R-MMU-5332993
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0030139	endocytic vesicle	ISO	J:164563
Cellular Component	GO:0005768	endosome	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:186896
Cellular Component	GO:0030027	lamellipodium	IDA	J:189982
Cellular Component	GO:0005770	late endosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0098857	membrane microdomain	IDA	J:186896
Cellular Component	GO:0005874	microtubule	IDA	J:160150
Cellular Component	GO:0005634	nucleus	IDA	J:186896
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:186896
Cellular Component	GO:0005886	plasma membrane	IDA	J:217139
Cellular Component	GO:0005886	plasma membrane	IDA	J:182257
Cellular Component	GO:0042383	sarcolemma	IDA	J:83126
Cellular Component	GO:0042383	sarcolemma	ISO	J:164563
Cellular Component	GO:0042383	sarcolemma	IDA	J:108320
Cellular Component	GO:0042383	sarcolemma	IDA	J:87169
Cellular Component	GO:0042383	sarcolemma	IDA	J:104461
Cellular Component	GO:0042383	sarcolemma	IDA	J:217139
Cellular Component	GO:0030315	T-tubule	ISO	J:164563
Cellular Component	GO:0030315	T-tubule	IBA	J:265628
Cellular Component	GO:0030315	T-tubule	IDA	J:205500
Cellular Component	GO:0030315	T-tubule	IDA	J:217139
Cellular Component	GO:0030315	T-tubule	IDA	J:104461
Biological Process	GO:0001525	angiogenesis	IMP	J:186896
Biological Process	GO:0001525	angiogenesis	IMP	J:186896
Biological Process	GO:0071470	cellular response to osmotic stress	IMP	J:205500
Biological Process	GO:0001816	cytokine production	IMP	J:148110
Biological Process	GO:0045444	fat cell differentiation	IMP	J:210966
Biological Process	GO:0006071	glycerol metabolic process	IMP	J:206183
Biological Process	GO:0006071	glycerol metabolic process	IGI	J:206183
Biological Process	GO:0019915	lipid storage	IMP	J:210966
Biological Process	GO:0002281	macrophage activation involved in immune response	IBA	J:265628
Biological Process	GO:0002281	macrophage activation involved in immune response	IMP	J:132272
Biological Process	GO:0002281	macrophage activation involved in immune response	ISO	J:132272
Biological Process	GO:0002280	monocyte activation involved in immune response	IBA	J:265628
Biological Process	GO:0002280	monocyte activation involved in immune response	IMP	J:132272
Biological Process	GO:0002280	monocyte activation involved in immune response	ISO	J:132272
Biological Process	GO:0055001	muscle cell development	IMP	J:206183
Biological Process	GO:0055001	muscle cell development	IMP	J:210966
Biological Process	GO:0055001	muscle cell development	IGI	J:206183
Biological Process	GO:0014902	myotube differentiation	ISO	J:182257
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:132272
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:132272
Biological Process	GO:1901842	negative regulation of high voltage-gated calcium channel activity	IMP	J:205500
Biological Process	GO:0007026	negative regulation of microtubule depolymerization	ISO	J:182257
Biological Process	GO:0050765	negative regulation of phagocytosis	IBA	J:265628
Biological Process	GO:0050765	negative regulation of phagocytosis	ISO	J:132272
Biological Process	GO:0050765	negative regulation of phagocytosis	IMP	J:132272
Biological Process	GO:0050765	negative regulation of phagocytosis	IMP	J:132272
Biological Process	GO:0032091	negative regulation of protein binding	IMP	J:182257
Biological Process	GO:0042177	negative regulation of protein catabolic process	IMP	J:186896
Biological Process	GO:1902915	negative regulation of protein polyubiquitination	IMP	J:186896
Biological Process	GO:1904428	negative regulation of tubulin deacetylation	ISO	J:182257
Biological Process	GO:1904428	negative regulation of tubulin deacetylation	IMP	J:182257
Biological Process	GO:0001778	plasma membrane repair	IMP	J:83126
Biological Process	GO:0001778	plasma membrane repair	IBA	J:265628
Biological Process	GO:0001778	plasma membrane repair	IDA	J:217139
Biological Process	GO:0001778	plasma membrane repair	IDA	J:87169
Biological Process	GO:0045785	positive regulation of cell adhesion	IMP	J:186896
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	IMP	J:186896
Biological Process	GO:0090023	positive regulation of neutrophil chemotaxis	IMP	J:148110
Biological Process	GO:0030163	protein catabolic process	IMP	J:186896
Biological Process	GO:0000209	protein polyubiquitination	IMP	J:186896
Biological Process	GO:0090279	regulation of calcium ion import	IMP	J:205500
Biological Process	GO:0007519	skeletal muscle tissue development	IDA	J:182257
Biological Process	GO:0007519	skeletal muscle tissue development	ISO	J:182257
Biological Process	GO:0043403	skeletal muscle tissue regeneration	IMP	J:148110
Biological Process	GO:0033292	T-tubule organization	IBA	J:265628
Biological Process	GO:0033292	T-tubule organization	IGI	J:206183
Biological Process	GO:0033292	T-tubule organization	IMP	J:205500
Biological Process	GO:0006906	vesicle fusion	IMP	J:83126
Biological Process	GO:0006906	vesicle fusion	IBA	J:265628