GO Annotations Graph

• Symbol: Casp8ap2
• Name: caspase 8 associated protein 2
• ID: MGI:1349399

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	IDA	J:55798
Molecular Function	GO:0042802	identical protein binding	IDA	J:55798
Molecular Function	GO:0002020	protease binding	IPI	J:196105
Molecular Function	GO:0005515	protein binding	IPI	J:55798
Molecular Function	GO:0005515	protein binding	IPI	J:55798
Molecular Function	GO:0005515	protein binding	IPI	J:55798
Molecular Function	GO:0032184	SUMO polymer binding	ISO	J:164563
Molecular Function	GO:0003714	transcription corepressor activity	ISO	J:164563
Molecular Function	GO:0003714	transcription corepressor activity	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0016605	PML body	ISO	J:164563
Cellular Component	GO:0016605	PML body	IBA	J:265628
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	IBA	J:265628
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	IDA	J:55798
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0097190	apoptotic signaling pathway	IEA	J:72247
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	ISO	J:164563
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	IBA	J:265628
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	IDA	J:55798
Biological Process	GO:0036337	Fas signaling pathway	ISO	J:164563
Biological Process	GO:0036337	Fas signaling pathway	IBA	J:265628