GO Annotations Graph

• Symbol: Foxl2
• Name: forkhead box L2
• ID: MGI:1349428

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:85559
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:85559
Molecular Function	GO:0003700	DNA-binding transcription factor activity	TAS	J:48144
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:85559
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0030331	nuclear estrogen receptor binding	IPI	J:157316
Molecular Function	GO:0030331	nuclear estrogen receptor binding	IPI	J:157008
Molecular Function	GO:0005515	protein binding	IPI	J:114729
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:85559
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	IEA	J:72247
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0031624	ubiquitin conjugating enzyme binding	ISO	J:164563
Cellular Component	GO:0090543	Flemming body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:157316
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:179634
Cellular Component	GO:0005634	nucleus	IDA	J:90371
Biological Process	GO:0009653	anatomical structure morphogenesis	IBA	J:265628
Biological Process	GO:0006309	apoptotic DNA fragmentation	ISO	J:164563
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0048048	embryonic eye morphogenesis	IMP	J:90371
Biological Process	GO:0002074	extraocular skeletal muscle development	ISO	J:164563
Biological Process	GO:0008585	female gonad development	IGI	J:214944
Biological Process	GO:0019101	female somatic sex determination	IMP	J:99790
Biological Process	GO:0060014	granulosa cell differentiation	IMP	J:87737
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:178424
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:178424
Biological Process	GO:0001541	ovarian follicle development	ISO	J:164563
Biological Process	GO:0001541	ovarian follicle development	IMP	J:90371
Biological Process	GO:0001541	ovarian follicle development	IGI	J:214944
Biological Process	GO:0001541	ovarian follicle development	IMP	J:87737
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:73065
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0046881	positive regulation of follicle-stimulating hormone secretion	IGI	J:214944
Biological Process	GO:0033686	positive regulation of luteinizing hormone secretion	IGI	J:214944
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:214944
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:85559
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0007338	single fertilization	IGI	J:214944
Biological Process	GO:0060065	uterus development	IGI	J:214944