GO Annotations Graph

• Symbol: Cln8
• Name: CLN8 transmembrane ER and ERGIC protein
• ID: MGI:1349447

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0097001	ceramide binding	ISO	J:164563
Molecular Function	GO:0097001	ceramide binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:235261
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:235261
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Biological Process	GO:0008344	adult locomotory behavior	IMP	J:107789
Biological Process	GO:0007628	adult walking behavior	IMP	J:25748
Biological Process	GO:0007628	adult walking behavior	IMP	J:55254
Biological Process	GO:0007628	adult walking behavior	IMP	J:121249
Biological Process	GO:0007628	adult walking behavior	IMP	J:12816
Biological Process	GO:0007628	adult walking behavior	IMP	J:8492
Biological Process	GO:0007628	adult walking behavior	IMP	J:52561
Biological Process	GO:0006915	apoptotic process	IMP	J:116862
Biological Process	GO:0008306	associative learning	IMP	J:98844
Biological Process	GO:0006672	ceramide metabolic process	ISO	J:164563
Biological Process	GO:0008203	cholesterol metabolic process	ISO	J:164563
Biological Process	GO:0051935	glutamate reuptake	IMP	J:47141
Biological Process	GO:0051935	glutamate reuptake	IMP	J:4191
Biological Process	GO:0055088	lipid homeostasis	IBA	J:265628
Biological Process	GO:0007040	lysosome organization	IMP	J:17600
Biological Process	GO:0007040	lysosome organization	IMP	J:53928
Biological Process	GO:0007040	lysosome organization	IMP	J:17522
Biological Process	GO:0007040	lysosome organization	IMP	J:17522
Biological Process	GO:0007040	lysosome organization	IMP	J:17600
Biological Process	GO:0007040	lysosome organization	IMP	J:17600
Biological Process	GO:0007040	lysosome organization	IMP	J:17522
Biological Process	GO:0007040	lysosome organization	IMP	J:17522
Biological Process	GO:0007040	lysosome organization	IMP	J:17600
Biological Process	GO:0007040	lysosome organization	IMP	J:17600
Biological Process	GO:0007040	lysosome organization	IMP	J:17600
Biological Process	GO:0007040	lysosome organization	IMP	J:17522
Biological Process	GO:0007040	lysosome organization	IMP	J:17600
Biological Process	GO:0007040	lysosome organization	IMP	J:23643
Biological Process	GO:0007040	lysosome organization	IMP	J:17600
Biological Process	GO:0007040	lysosome organization	IMP	J:17600
Biological Process	GO:0007040	lysosome organization	IMP	J:17600
Biological Process	GO:0009057	macromolecule catabolic process	IMP	J:112499
Biological Process	GO:0007006	mitochondrial membrane organization	IMP	J:39062
Biological Process	GO:0050881	musculoskeletal movement	IMP	J:121249
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:116862
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:116862
Biological Process	GO:0051348	negative regulation of transferase activity	IMP	J:35599
Biological Process	GO:0007399	nervous system development	ISO	J:164563
Biological Process	GO:0060052	neurofilament cytoskeleton organization	IMP	J:121249
Biological Process	GO:0050885	neuromuscular process controlling balance	IMP	J:52561
Biological Process	GO:0050884	neuromuscular process controlling posture	IMP	J:121249
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:116862
Biological Process	GO:0006644	phospholipid metabolic process	ISO	J:164563
Biological Process	GO:0006644	phospholipid metabolic process	IMP	J:42419
Biological Process	GO:0045494	photoreceptor cell maintenance	IMP	J:42641
Biological Process	GO:0045494	photoreceptor cell maintenance	IMP	J:116862
Biological Process	GO:0030163	protein catabolic process	IMP	J:4750
Biological Process	GO:0019538	protein metabolic process	IMP	J:624
Biological Process	GO:0008361	regulation of cell size	IMP	J:116862
Biological Process	GO:0060041	retina development in camera-type eye	IMP	J:166679
Biological Process	GO:0060041	retina development in camera-type eye	IMP	J:116862
Biological Process	GO:0097473	retinal rod cell apoptotic process	IMP	J:116862
Biological Process	GO:0035176	social behavior	IMP	J:107789
Biological Process	GO:0021523	somatic motor neuron differentiation	IMP	J:166679
Biological Process	GO:0021522	spinal cord motor neuron differentiation	IMP	J:121249
Biological Process	GO:0007601	visual perception	IMP	J:19328
Biological Process	GO:0007601	visual perception	IMP	J:12816
Biological Process	GO:0007601	visual perception	IMP	J:25748
Biological Process	GO:0007601	visual perception	IMP	J:17934