GO Annotations Graph

• Symbol: Adh4
• Name: alcohol dehydrogenase 4 (class II), pi polypeptide
• ID: MGI:1349472

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004022	alcohol dehydrogenase (NAD+) activity	ISO	J:155856
Molecular Function	GO:0004022	alcohol dehydrogenase (NAD+) activity	ISO	J:164563
Molecular Function	GO:0004022	alcohol dehydrogenase (NAD+) activity	IDA	J:6249
Molecular Function	GO:0004022	alcohol dehydrogenase (NAD+) activity	IDA	J:6249
Molecular Function	GO:0004022	alcohol dehydrogenase (NAD+) activity	IDA	J:6249
Molecular Function	GO:0004024	alcohol dehydrogenase activity, zinc-dependent	ISO	J:164563
Molecular Function	GO:0004024	alcohol dehydrogenase activity, zinc-dependent	IBA	J:265628
Molecular Function	GO:0004024	alcohol dehydrogenase activity, zinc-dependent	IDA	J:58011
Molecular Function	GO:0004032	alditol:NADP+ 1-oxidoreductase activity	IDA	J:58011
Molecular Function	GO:0005503	all-trans retinal binding	ISO	J:164563
Molecular Function	GO:0019115	benzaldehyde dehydrogenase [NAD(P)+] activity	ISO	J:164563
Molecular Function	GO:0035276	ethanol binding	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0051287	NAD binding	ISO	J:164563
Molecular Function	GO:0051287	NAD binding	ISO	J:155856
Molecular Function	GO:0004745	NAD-retinol dehydrogenase activity	ISO	J:164563
Molecular Function	GO:0003960	NADPH:quinone reductase activity	IDA	J:58011
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:72247
Molecular Function	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	ISO	J:164563
Molecular Function	GO:0019841	retinol binding	ISO	J:164563
Molecular Function	GO:0051903	S-(hydroxymethyl)glutathione dehydrogenase activity	IBA	J:265628
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Biological Process	GO:0046164	alcohol catabolic process	IDA	J:58011
Biological Process	GO:0006066	alcohol metabolic process	ISO	J:164563
Biological Process	GO:0006081	cellular aldehyde metabolic process	ISO	J:164563
Biological Process	GO:0006081	cellular aldehyde metabolic process	IDA	J:58011
Biological Process	GO:0006067	ethanol metabolic process	IDA	J:6249
Biological Process	GO:0006067	ethanol metabolic process	IDA	J:6249
Biological Process	GO:0006067	ethanol metabolic process	IDA	J:6249
Biological Process	GO:0006069	ethanol oxidation	ISO	J:164563
Biological Process	GO:0006069	ethanol oxidation	ISO	J:155856
Biological Process	GO:0010430	fatty acid omega-oxidation	IDA	J:277852
Biological Process	GO:0010430	fatty acid omega-oxidation	ISO	J:164563
Biological Process	GO:0046294	formaldehyde catabolic process	IBA	J:265628
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:1901661	quinone metabolic process	IDA	J:58011
Biological Process	GO:0001523	retinoid metabolic process	ISO	J:164563
Biological Process	GO:0042572	retinol metabolic process	ISO	J:164563