GO Annotations Graph

• Symbol: Tob1
• Name: transducer of ErbB-2.1
• ID: MGI:1349721

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:168702
Molecular Function	GO:0005515	protein binding	IPI	J:66504
Molecular Function	GO:0005515	protein binding	IPI	J:66504
Molecular Function	GO:0005515	protein binding	IPI	J:66504
Molecular Function	GO:0005515	protein binding	IPI	J:66504
Molecular Function	GO:0030971	receptor tyrosine kinase binding	ISO	J:164563
Molecular Function	GO:0046332	SMAD binding	IDA	J:66504
Molecular Function	GO:0003714	transcription corepressor activity	IBA	J:265628
Molecular Function	GO:0003714	transcription corepressor activity	IDA	J:66504
Cellular Component	GO:0030014	CCR4-NOT complex	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:66504
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	IDA	J:66504
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0060212	negative regulation of nuclear-transcribed mRNA poly(A) tail shortening	ISO	J:164563
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	IMP	J:66504
Biological Process	GO:0017148	negative regulation of translation	ISO	J:164563
Biological Process	GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	ISO	J:164563
Biological Process	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	ISO	J:164563
Biological Process	GO:0010468	regulation of gene expression	IBA	J:265628
Biological Process	GO:0060390	regulation of SMAD protein signal transduction	IDA	J:66504