Tcirg1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Tcirg1
T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3
MGI:1350931

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051117	ATPase binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:278051
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0005770	late endosome	IDA	J:150327
Cellular Component	GO:0005770	late endosome	IDA	J:83868
Cellular Component	GO:0005764	lysosome	IDA	J:150327
Cellular Component	GO:0005764	lysosome	IDA	J:83868
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005634	nucleus	IDA	J:183295
Cellular Component	GO:0045335	phagocytic vesicle	IDA	J:150327
Cellular Component	GO:0030670	phagocytic vesicle membrane	IDA	J:150327
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:61380
Cellular Component	GO:0005886	plasma membrane	IDA	J:83868
Cellular Component	GO:0030667	secretory granule membrane	IDA	J:116082
Cellular Component	GO:0016471	vacuolar proton-transporting V-type ATPase complex	IBA	J:265628
Biological Process	GO:0006915	apoptotic process	IMP	J:274229
Biological Process	GO:0006915	apoptotic process	IMP	J:196503
Biological Process	GO:0000045	autophagosome assembly	IMP	J:274229
Biological Process	GO:0006914	autophagy	IMP	J:274229
Biological Process	GO:0030183	B cell differentiation	IMP	J:93047
Biological Process	GO:0030183	B cell differentiation	IMP	J:111910
Biological Process	GO:0030183	B cell differentiation	IMP	J:92730
Biological Process	GO:0045453	bone resorption	IMP	J:274229
Biological Process	GO:0045453	bone resorption	IMP	J:194087
Biological Process	GO:0045453	bone resorption	IMP	J:196503
Biological Process	GO:0045453	bone resorption	IMP	J:180981
Biological Process	GO:0045453	bone resorption	IMP	J:143799
Biological Process	GO:0071345	cellular response to cytokine stimulus	IMP	J:92730
Biological Process	GO:0097188	dentin mineralization	IMP	J:193881
Biological Process	GO:0070166	enamel mineralization	IMP	J:193881
Biological Process	GO:0030010	establishment of cell polarity	IMP	J:274229
Biological Process	GO:0051650	establishment of vesicle localization	IMP	J:278051
Biological Process	GO:0010467	gene expression	IMP	J:274229
Biological Process	GO:0061484	hematopoietic stem cell homeostasis	IMP	J:182505
Biological Process	GO:0048872	homeostasis of number of cells	IMP	J:180981
Biological Process	GO:0048872	homeostasis of number of cells	IMP	J:182505
Biological Process	GO:0016064	immunoglobulin mediated immune response	IMP	J:108136
Biological Process	GO:0002377	immunoglobulin production	IMP	J:92730
Biological Process	GO:0006954	inflammatory response	IMP	J:194087
Biological Process	GO:0006874	intracellular calcium ion homeostasis	IMP	J:151255
Biological Process	GO:0051452	intracellular pH reduction	IMP	J:274229
Biological Process	GO:0016236	macroautophagy	IMP	J:199115
Biological Process	GO:0035709	memory T cell activation	IMP	J:108136
Biological Process	GO:0030099	myeloid cell differentiation	IMP	J:93047
Biological Process	GO:0042476	odontogenesis	IMP	J:183295
Biological Process	GO:0021554	optic nerve development	IMP	J:162757
Biological Process	GO:0001503	ossification	IMP	J:180981
Biological Process	GO:0030316	osteoclast differentiation	IMP	J:274229
Biological Process	GO:0030316	osteoclast differentiation	IMP	J:143799
Biological Process	GO:0030316	osteoclast differentiation	IMP	J:196503
Biological Process	GO:0030316	osteoclast differentiation	IMP	J:183295
Biological Process	GO:0030316	osteoclast differentiation	IMP	J:194087
Biological Process	GO:0002158	osteoclast proliferation	IMP	J:180981
Biological Process	GO:0045851	pH reduction	IMP	J:196087
Biological Process	GO:0045851	pH reduction	IMP	J:151255
Biological Process	GO:0090383	phagosome acidification	IMP	J:150327
Biological Process	GO:0007039	protein catabolic process in the vacuole	IMP	J:199115
Biological Process	GO:0033365	protein localization to organelle	IMP	J:278051
Biological Process	GO:0010468	regulation of gene expression	IMP	J:92730
Biological Process	GO:0010468	regulation of gene expression	IMP	J:196087
Biological Process	GO:0010468	regulation of gene expression	IMP	J:196503
Biological Process	GO:0050796	regulation of insulin secretion	IMP	J:116082
Biological Process	GO:0045667	regulation of osteoblast differentiation	IMP	J:182505
Biological Process	GO:0010155	regulation of proton transport	IMP	J:196503
Biological Process	GO:0010272	response to silver ion	IMP	J:92730
Biological Process	GO:0060041	retina development in camera-type eye	IMP	J:162757
Biological Process	GO:0031529	ruffle organization	IMP	J:274229
Biological Process	GO:0030217	T cell differentiation	IMP	J:92730
Biological Process	GO:0043029	T cell homeostasis	IMP	J:194087
Biological Process	GO:0035711	T-helper 1 cell activation	IMP	J:93047
Biological Process	GO:0044691	tooth eruption	IMP	J:183295
Biological Process	GO:0032609	type II interferon production	IMP	J:93047
Biological Process	GO:0007035	vacuolar acidification	IBA	J:265628

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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