GO Annotations Graph

• Symbol: Slamf1
• Name: signaling lymphocytic activation molecule family member 1
• ID: MGI:1351314

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IDA	J:229624
Molecular Function	GO:0005515	protein binding	IPI	J:111421
Molecular Function	GO:0005515	protein binding	IPI	J:145969
Molecular Function	GO:0005515	protein binding	IPI	J:185616
Molecular Function	GO:0005515	protein binding	IPI	J:106459
Molecular Function	GO:0005515	protein binding	IPI	J:185616
Molecular Function	GO:0005515	protein binding	IPI	J:106459
Molecular Function	GO:0005515	protein binding	IPI	J:185616
Molecular Function	GO:0005515	protein binding	IPI	J:64014
Molecular Function	GO:0042169	SH2 domain binding	ISO	J:164563
Molecular Function	GO:0038023	signaling receptor activity	IBA	J:265628
Molecular Function	GO:0038023	signaling receptor activity	IDA	J:229624
Cellular Component	GO:0009986	cell surface	IDA	J:232381
Cellular Component	GO:0009897	external side of plasma membrane	IBA	J:265628
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:145577
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:163607
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:224867
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:203580
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0045335	phagocytic vesicle	IDA	J:185616
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0002250	adaptive immune response	IEA	J:60000
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0002232	leukocyte chemotaxis involved in inflammatory response	IMP	J:229624
Biological Process	GO:0046649	lymphocyte activation	IEA	J:72247
Biological Process	GO:0002277	myeloid dendritic cell activation involved in immune response	ISO	J:164563
Biological Process	GO:0001779	natural killer cell differentiation	IMP	J:127620
Biological Process	GO:0001787	natural killer cell proliferation	IMP	J:127620
Biological Process	GO:2000349	negative regulation of CD40 signaling pathway	ISO	J:164563
Biological Process	GO:0032695	negative regulation of interleukin-12 production	ISO	J:164563
Biological Process	GO:0032715	negative regulation of interleukin-6 production	ISO	J:164563
Biological Process	GO:0002725	negative regulation of T cell cytokine production	IDA	J:227397
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	ISO	J:164563
Biological Process	GO:0032689	negative regulation of type II interferon production	IDA	J:227397
Biological Process	GO:0006909	phagocytosis	IEA	J:60000
Biological Process	GO:0042104	positive regulation of activated T cell proliferation	IDA	J:227465
Biological Process	GO:2000510	positive regulation of dendritic cell chemotaxis	IMP	J:229624
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:164563
Biological Process	GO:0046330	positive regulation of JNK cascade	ISO	J:164563
Biological Process	GO:0010759	positive regulation of macrophage chemotaxis	IMP	J:229624
Biological Process	GO:0010759	positive regulation of macrophage chemotaxis	IMP	J:232381
Biological Process	GO:2000556	positive regulation of T-helper 1 cell cytokine production	IDA	J:227465
Biological Process	GO:0032729	positive regulation of type II interferon production	IDA	J:227465
Biological Process	GO:0032729	positive regulation of type II interferon production	IBA	J:265628
Biological Process	GO:0050790	regulation of catalytic activity	IMP	J:185616
Biological Process	GO:0031338	regulation of vesicle fusion	IMP	J:185616
Biological Process	GO:0031338	regulation of vesicle fusion	IMP	J:185616