GO Annotations Graph

• Symbol: Grm7
• Name: glutamate receptor, metabotropic 7
• ID: MGI:1351344

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001640	adenylate cyclase inhibiting G protein-coupled glutamate receptor activity	ISO	J:155856
Molecular Function	GO:0010855	adenylate cyclase inhibitor activity	ISO	J:164563
Molecular Function	GO:0010855	adenylate cyclase inhibitor activity	ISO	J:164563
Molecular Function	GO:0005246	calcium channel regulator activity	IDA	J:73174
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0048306	calcium-dependent protein binding	ISO	J:155856
Molecular Function	GO:0005516	calmodulin binding	ISO	J:155856
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0016595	glutamate binding	ISO	J:155856
Molecular Function	GO:0016595	glutamate binding	ISO	J:164563
Molecular Function	GO:0008066	glutamate receptor activity	ISO	J:164563
Molecular Function	GO:0001642	group III metabotropic glutamate receptor activity	ISO	J:164563
Molecular Function	GO:0001642	group III metabotropic glutamate receptor activity	ISO	J:155856
Molecular Function	GO:0001642	group III metabotropic glutamate receptor activity	IBA	J:265628
Molecular Function	GO:0001642	group III metabotropic glutamate receptor activity	TAS	J:52411
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0030165	PDZ domain binding	TAS	J:114768
Molecular Function	GO:0030165	PDZ domain binding	ISO	J:155856
Molecular Function	GO:0046983	protein dimerization activity	ISO	J:164563
Molecular Function	GO:0070905	serine binding	ISO	J:164563
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IDA	J:114768
Cellular Component	GO:0032279	asymmetric synapse	ISO	J:155856
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0043679	axon terminus	ISO	J:155856
Cellular Component	GO:0005938	cell cortex	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:164563
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0043198	dendritic shaft	ISO	J:155856
Cellular Component	GO:0098982	GABA-ergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:114768
Cellular Component	GO:0098978	glutamatergic synapse	EXP	J:114768
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:114768
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0048786	presynaptic active zone	ISO	J:155856
Cellular Component	GO:0048787	presynaptic active zone membrane	ISO	J:155856
Cellular Component	GO:0048787	presynaptic active zone membrane	TAS	J:114768
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:114768
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0043235	receptor complex	ISO	J:194542
Cellular Component	GO:0005791	rough endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0043195	terminal bouton	ISO	J:155856
Biological Process	GO:0007196	adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway	ISO	J:155856
Biological Process	GO:0007196	adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0030534	adult behavior	IMP	J:89656
Biological Process	GO:0008306	associative learning	IMP	J:109594
Biological Process	GO:0061564	axon development	ISO	J:164563
Biological Process	GO:0001662	behavioral fear response	IMP	J:52411
Biological Process	GO:0007268	chemical synaptic transmission	ISO	J:164563
Biological Process	GO:0007268	chemical synaptic transmission	IDA	J:114768
Biological Process	GO:0001661	conditioned taste aversion	IMP	J:52411
Biological Process	GO:0007216	G protein-coupled glutamate receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:72247
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:60000
Biological Process	GO:0070085	glycosylation	ISO	J:164563
Biological Process	GO:0007613	memory	IMP	J:114435
Biological Process	GO:0007613	memory	IMP	J:109594
Biological Process	GO:0033555	multicellular organismal response to stress	IMP	J:89656
Biological Process	GO:0014050	negative regulation of glutamate secretion	ISO	J:155856
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	ISO	J:155856
Biological Process	GO:0050877	nervous system process	IMP	J:114435
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	EXP	J:114768
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IDA	J:114768
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IDA	J:114768
Biological Process	GO:1901214	regulation of neuron death	TAS	J:114768
Biological Process	GO:0051966	regulation of synaptic transmission, glutamatergic	IBA	J:265628
Biological Process	GO:0050896	response to stimulus	IEA	J:60000
Biological Process	GO:0007605	sensory perception of sound	ISO	J:164563
Biological Process	GO:0007614	short-term memory	IMP	J:96176
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0019226	transmission of nerve impulse	IMP	J:72691