GO Annotations Graph

• Symbol: Atic
• Name: 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
• ID: MGI:1351352

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0003824	catalytic activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0003937	IMP cyclohydrolase activity	ISO	J:155856
Molecular Function	GO:0003937	IMP cyclohydrolase activity	IBA	J:265628
Molecular Function	GO:0003937	IMP cyclohydrolase activity	ISO	J:306655
Molecular Function	GO:0003937	IMP cyclohydrolase activity	ISO	J:155856
Molecular Function	GO:0003937	IMP cyclohydrolase activity	IMP	J:306719
Molecular Function	GO:0003937	IMP cyclohydrolase activity	ISO	J:306655
Molecular Function	GO:0003937	IMP cyclohydrolase activity	ISO	J:306655
Molecular Function	GO:0003937	IMP cyclohydrolase activity	ISO	J:306655
Molecular Function	GO:0004643	phosphoribosylaminoimidazolecarboxamide formyltransferase activity	ISO	J:155856
Molecular Function	GO:0004643	phosphoribosylaminoimidazolecarboxamide formyltransferase activity	IBA	J:265628
Molecular Function	GO:0004643	phosphoribosylaminoimidazolecarboxamide formyltransferase activity	IMP	J:306654
Molecular Function	GO:0004643	phosphoribosylaminoimidazolecarboxamide formyltransferase activity	ISO	J:155856
Molecular Function	GO:0004643	phosphoribosylaminoimidazolecarboxamide formyltransferase activity	IMP	J:306654
Molecular Function	GO:0004643	phosphoribosylaminoimidazolecarboxamide formyltransferase activity	IMP	J:306654
Molecular Function	GO:0004643	phosphoribosylaminoimidazolecarboxamide formyltransferase activity	IMP	J:306654
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0044208	'de novo' AMP biosynthetic process	IMP	J:306654
Biological Process	GO:0044208	'de novo' AMP biosynthetic process	ISO	J:306655
Biological Process	GO:0006189	'de novo' IMP biosynthetic process	ISO	J:155856
Biological Process	GO:0006189	'de novo' IMP biosynthetic process	IBA	J:265628
Biological Process	GO:0006189	'de novo' IMP biosynthetic process	IMP	J:306654
Biological Process	GO:0006189	'de novo' IMP biosynthetic process	ISO	J:306655
Biological Process	GO:0097294	'de novo' XMP biosynthetic process	IMP	J:306654
Biological Process	GO:0097294	'de novo' XMP biosynthetic process	ISO	J:306655
Biological Process	GO:0098761	cellular response to interleukin-7	IDA	J:260356
Biological Process	GO:0046452	dihydrofolate metabolic process	ISO	J:155856
Biological Process	GO:0006177	GMP biosynthetic process	ISO	J:306655
Biological Process	GO:0006177	GMP biosynthetic process	IMP	J:306654
Biological Process	GO:0008152	metabolic process	IEA	J:60000
Biological Process	GO:0009116	nucleoside metabolic process	ISO	J:155856
Biological Process	GO:0006164	purine nucleotide biosynthetic process	IEA	J:60000
Biological Process	GO:0006164	purine nucleotide biosynthetic process	IEA	J:72247
Biological Process	GO:0009259	ribonucleotide metabolic process	ISO	J:155856
Biological Process	GO:0046654	tetrahydrofolate biosynthetic process	ISO	J:155856