GO Annotations Graph

• Symbol: Sytl4
• Name: synaptotagmin-like 4
• ID: MGI:1351606

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0042043	neurexin family protein binding	IDA	J:68115
Molecular Function	GO:0042043	neurexin family protein binding	IBA	J:265628
Molecular Function	GO:0005543	phospholipid binding	IDA	J:57922
Molecular Function	GO:0005515	protein binding	IPI	J:75312
Molecular Function	GO:0005515	protein binding	IPI	J:155185
Molecular Function	GO:0005515	protein binding	IPI	J:75312
Molecular Function	GO:0005515	protein binding	IPI	J:75312
Molecular Function	GO:0005515	protein binding	IPI	J:83162
Molecular Function	GO:0005515	protein binding	IPI	J:83162
Molecular Function	GO:0005515	protein binding	IPI	J:83162
Molecular Function	GO:0005515	protein binding	IPI	J:83162
Molecular Function	GO:0031267	small GTPase binding	IEA	J:72247
Molecular Function	GO:0008270	zinc ion binding	NAS	J:69335
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005768	endosome	ISO	J:164563
Cellular Component	GO:0070382	exocytic vesicle	IBA	J:265628
Cellular Component	GO:0019898	extrinsic component of membrane	IDA	J:68115
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0030141	secretory granule	IDA	J:57922
Cellular Component	GO:0030667	secretory granule membrane	ISO	J:155856
Biological Process	GO:0006887	exocytosis	IBA	J:265628
Biological Process	GO:0006887	exocytosis	IDA	J:83162
Biological Process	GO:0030073	insulin secretion	IMP	J:129731
Biological Process	GO:0006886	intracellular protein transport	IEA	J:72247
Biological Process	GO:0032418	lysosome localization	ISO	J:164563
Biological Process	GO:0071985	multivesicular body sorting pathway	ISO	J:164563
Biological Process	GO:0046676	negative regulation of insulin secretion	IMP	J:129731
Biological Process	GO:0001778	plasma membrane repair	ISO	J:164563
Biological Process	GO:0045921	positive regulation of exocytosis	ISO	J:164563
Biological Process	GO:0050714	positive regulation of protein secretion	ISO	J:164563
Biological Process	GO:1905684	regulation of plasma membrane repair	ISO	J:164563