GO Annotations Graph

• Symbol: Abca3
• Name: ATP-binding cassette, sub-family A member 3
• ID: MGI:1351617

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0140359	ABC-type transporter activity	IEA	J:72247
Molecular Function	GO:0008559	ABC-type xenobiotic transporter activity	ISO	J:164563
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0016887	ATP hydrolysis activity	ISO	J:164563
Molecular Function	GO:0140326	ATPase-coupled intramembrane lipid transporter activity	IEA	J:72245
Molecular Function	GO:0042626	ATPase-coupled transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0005319	lipid transporter activity	IBA	J:265628
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0140345	phosphatidylcholine flippase activity	ISO	J:164563
Molecular Function	GO:0120019	phosphatidylcholine transfer activity	ISO	J:164563
Cellular Component	GO:0097208	alveolar lamellar body	ISO	J:73065
Cellular Component	GO:0097233	alveolar lamellar body membrane	ISO	J:164563
Cellular Component	GO:0097233	alveolar lamellar body membrane	ISO	J:155856
Cellular Component	GO:0097233	alveolar lamellar body membrane	IDA	J:297313
Cellular Component	GO:0097233	alveolar lamellar body membrane	IDA	J:88433
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	ISO	J:164563
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IBA	J:265628
Cellular Component	GO:0042599	lamellar body	ISO	J:164563
Cellular Component	GO:0097232	lamellar body membrane	ISO	J:164563
Cellular Component	GO:0005770	late endosome	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005886	plasma membrane	ISO	J:73065
Biological Process	GO:0006869	lipid transport	IBA	J:265628
Biological Process	GO:0030324	lung development	IMP	J:124809
Biological Process	GO:0030324	lung development	IMP	J:278537
Biological Process	GO:0070925	organelle assembly	IMP	J:124809
Biological Process	GO:0046470	phosphatidylcholine metabolic process	ISO	J:164563
Biological Process	GO:0046470	phosphatidylcholine metabolic process	IMP	J:121155
Biological Process	GO:0046471	phosphatidylglycerol metabolic process	IMP	J:120296
Biological Process	GO:0046471	phosphatidylglycerol metabolic process	IMP	J:121155
Biological Process	GO:0055091	phospholipid homeostasis	IMP	J:278537
Biological Process	GO:0015914	phospholipid transport	ISO	J:164563
Biological Process	GO:0010875	positive regulation of cholesterol efflux	ISO	J:164563
Biological Process	GO:1902995	positive regulation of phospholipid efflux	ISO	J:164563
Biological Process	GO:2001140	positive regulation of phospholipid transport	ISO	J:164563
Biological Process	GO:0032464	positive regulation of protein homooligomerization	ISO	J:164563
Biological Process	GO:0046890	regulation of lipid biosynthetic process	IMP	J:278537
Biological Process	GO:0032368	regulation of lipid transport	IMP	J:278537
Biological Process	GO:0150172	regulation of phosphatidylcholine metabolic process	ISO	J:164563
Biological Process	GO:0043129	surfactant homeostasis	IMP	J:122736
Biological Process	GO:0043129	surfactant homeostasis	IMP	J:274491
Biological Process	GO:0043129	surfactant homeostasis	IMP	J:120296
Biological Process	GO:0043129	surfactant homeostasis	IMP	J:121155
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0006810	transport	ISO	J:73065
Biological Process	GO:0046618	xenobiotic export from cell	ISO	J:164563
Biological Process	GO:0006855	xenobiotic transmembrane transport	ISO	J:164563
Biological Process	GO:0042908	xenobiotic transport	ISO	J:164563