Abca7 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Abca7
ATP-binding cassette, sub-family A member 7
MGI:1351646

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0140359	ABC-type transporter activity	IEA	J:72247
Molecular Function	GO:0034188	apolipoprotein A-I receptor activity	ISO	J:164563
Molecular Function	GO:0034188	apolipoprotein A-I receptor activity	IDA	J:207821
Molecular Function	GO:0034188	apolipoprotein A-I receptor activity	IBA	J:265628
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0042626	ATPase-coupled transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0140328	floppase activity	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0090554	phosphatidylcholine floppase activity	ISO	J:164563
Molecular Function	GO:0090554	phosphatidylcholine floppase activity	IBA	J:265628
Molecular Function	GO:0090556	phosphatidylserine floppase activity	ISO	J:164563
Molecular Function	GO:0090556	phosphatidylserine floppase activity	IBA	J:265628
Molecular Function	GO:0005548	phospholipid transporter activity	ISO	J:164563
Molecular Function	GO:0005548	phospholipid transporter activity	IDA	J:94706
Molecular Function	GO:0005515	protein binding	IPI	J:207821
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:94706
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	IDA	J:206915
Cellular Component	GO:0009986	cell surface	IDA	J:207821
Cellular Component	GO:0005737	cytoplasm	IDA	J:268026
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0097386	glial cell projection	IDA	J:268026
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005622	intracellular anatomical structure	IDA	J:94706
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IBA	J:265628
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0001891	phagocytic cup	IDA	J:112621
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0032587	ruffle membrane	IDA	J:112621
Biological Process	GO:0150094	amyloid-beta clearance by cellular catabolic process	IMP	J:268026
Biological Process	GO:0034205	amyloid-beta formation	ISO	J:164563
Biological Process	GO:0034205	amyloid-beta formation	IMP	J:225870
Biological Process	GO:0038027	apolipoprotein A-I-mediated signaling pathway	IMP	J:206915
Biological Process	GO:0038027	apolipoprotein A-I-mediated signaling pathway	IDA	J:207821
Biological Process	GO:0038027	apolipoprotein A-I-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0033344	cholesterol efflux	IMP	J:268026
Biological Process	GO:0033344	cholesterol efflux	ISO	J:164563
Biological Process	GO:0033344	cholesterol efflux	IBA	J:265628
Biological Process	GO:0034380	high-density lipoprotein particle assembly	ISO	J:164563
Biological Process	GO:0006869	lipid transport	IEA	J:60000
Biological Process	GO:0007613	memory	IMP	J:196282
Biological Process	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process	IDA	J:206916
Biological Process	GO:1902430	negative regulation of amyloid-beta formation	IDA	J:206916
Biological Process	GO:1902430	negative regulation of amyloid-beta formation	IMP	J:196282
Biological Process	GO:1902430	negative regulation of amyloid-beta formation	IMP	J:231748
Biological Process	GO:0045806	negative regulation of endocytosis	IMP	J:225870
Biological Process	GO:0043409	negative regulation of MAPK cascade	IMP	J:231748
Biological Process	GO:1903898	negative regulation of PERK-mediated unfolded protein response	IMP	J:231748
Biological Process	GO:0018149	peptide cross-linking	IDA	J:207821
Biological Process	GO:0006909	phagocytosis	IEA	J:60000
Biological Process	GO:0033700	phospholipid efflux	ISO	J:164563
Biological Process	GO:0033700	phospholipid efflux	IMP	J:268026
Biological Process	GO:0033700	phospholipid efflux	IBA	J:265628
Biological Process	GO:0033700	phospholipid efflux	IDA	J:94706
Biological Process	GO:0045332	phospholipid translocation	ISO	J:164563
Biological Process	GO:0044857	plasma membrane raft organization	IMP	J:269558
Biological Process	GO:1900223	positive regulation of amyloid-beta clearance	IMP	J:196282
Biological Process	GO:0010875	positive regulation of cholesterol efflux	IDA	J:206916
Biological Process	GO:1901076	positive regulation of engulfment of apoptotic cell	IMP	J:112621
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IMP	J:112621
Biological Process	GO:0050766	positive regulation of phagocytosis	IMP	J:268026
Biological Process	GO:0050766	positive regulation of phagocytosis	IMP	J:206915
Biological Process	GO:1902995	positive regulation of phospholipid efflux	IDA	J:207821
Biological Process	GO:2000010	positive regulation of protein localization to cell surface	IMP	J:269558
Biological Process	GO:0034504	protein localization to nucleus	IDA	J:206916
Biological Process	GO:1902991	regulation of amyloid precursor protein catabolic process	ISO	J:164563
Biological Process	GO:0019216	regulation of lipid metabolic process	IMP	J:231748
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0008542	visual learning	IMP	J:231748

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24