Trpm2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Trpm2
transient receptor potential cation channel, subfamily M, member 2
MGI:1351901

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0047631	ADP-ribose diphosphatase activity	IEA	J:72247
Molecular Function	GO:0005262	calcium channel activity	IEA	J:60000
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0015278	calcium-release channel activity	ISO	J:164563
Molecular Function	GO:0099604	ligand-gated calcium channel activity	ISO	J:164563
Molecular Function	GO:0099604	ligand-gated calcium channel activity	IMP	J:178425
Molecular Function	GO:0099604	ligand-gated calcium channel activity	IBA	J:265628
Molecular Function	GO:0005384	manganese ion transmembrane transporter activity	IDA	J:137259
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0072571	mono-ADP-D-ribose binding	ISO	J:164563
Molecular Function	GO:0005261	monoatomic cation channel activity	ISO	J:164563
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0005272	sodium channel activity	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	IDA	J:178425
Cellular Component	GO:0005765	lysosomal membrane	IDA	J:178425
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:178425
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:137259
Biological Process	GO:0098703	calcium ion import across plasma membrane	IMP	J:178425
Biological Process	GO:0098703	calcium ion import across plasma membrane	ISO	J:155856
Biological Process	GO:0097553	calcium ion transmembrane import into cytosol	ISO	J:164563
Biological Process	GO:0070588	calcium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0006816	calcium ion transport	IEA	J:60000
Biological Process	GO:0035584	calcium-mediated signaling using intracellular calcium source	IMP	J:178425
Biological Process	GO:0071277	cellular response to calcium ion	ISO	J:164563
Biological Process	GO:0070301	cellular response to hydrogen peroxide	ISO	J:164563
Biological Process	GO:0071415	cellular response to purine-containing compound	IMP	J:178425
Biological Process	GO:0071502	cellular response to temperature stimulus	IMP	J:235274
Biological Process	GO:0002407	dendritic cell chemotaxis	IMP	J:178425
Biological Process	GO:0097028	dendritic cell differentiation	IMP	J:178425
Biological Process	GO:0006828	manganese ion transport	IDA	J:137259
Biological Process	GO:0006812	monoatomic cation transport	IEA	J:72247
Biological Process	GO:0034220	monoatomic ion transmembrane transport	IEA	J:72247
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0032024	positive regulation of insulin secretion	ISO	J:155856
Biological Process	GO:1903223	positive regulation of oxidative stress-induced neuron death	ISO	J:155856
Biological Process	GO:0051289	protein homotetramerization	ISO	J:164563
Biological Process	GO:2000249	regulation of actin cytoskeleton reorganization	ISO	J:164563
Biological Process	GO:0051489	regulation of filopodium assembly	ISO	J:164563
Biological Process	GO:0051209	release of sequestered calcium ion into cytosol	IMP	J:178425
Biological Process	GO:0051209	release of sequestered calcium ion into cytosol	ISO	J:164563
Biological Process	GO:0051209	release of sequestered calcium ion into cytosol	IBA	J:265628
Biological Process	GO:0009408	response to heat	IMP	J:235274
Biological Process	GO:0033194	response to hydroperoxide	IDA	J:137259
Biological Process	GO:0006979	response to oxidative stress	IEA	J:72247
Biological Process	GO:0014074	response to purine-containing compound	ISO	J:164563
Biological Process	GO:0006814	sodium ion transport	IEA	J:60000
Biological Process	GO:0001659	temperature homeostasis	IMP	J:235274
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0071577	zinc ion transmembrane transport	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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