GO Annotations Graph

• Symbol: Abcc2
• Name: ATP-binding cassette, sub-family member 2
• ID: MGI:1352447

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015431	ABC-type glutathione S-conjugate transporter activity	ISO	J:164563
Molecular Function	GO:0015431	ABC-type glutathione S-conjugate transporter activity	ISO	J:155856
Molecular Function	GO:0008559	ABC-type xenobiotic transporter activity	ISO	J:155856
Molecular Function	GO:0008559	ABC-type xenobiotic transporter activity	ISO	J:164563
Molecular Function	GO:0042626	ATPase-coupled transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0042626	ATPase-coupled transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0015127	bilirubin transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015127	bilirubin transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:77485
Molecular Function	GO:0005515	protein binding	IPI	J:77485
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0042910	xenobiotic transmembrane transporter activity	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	IBA	J:265628
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:85619
Cellular Component	GO:0031526	brush border membrane	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0046581	intercellular canaliculus	IDA	J:77485
Cellular Component	GO:0046691	intracellular canaliculus	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:68661
Cellular Component	GO:0005886	plasma membrane	IDA	J:85619
Biological Process	GO:0016999	antibiotic metabolic process	ISO	J:155856
Biological Process	GO:1901086	benzylpenicillin metabolic process	ISO	J:155856
Biological Process	GO:0015721	bile acid and bile salt transport	ISO	J:164563
Biological Process	GO:0015723	bilirubin transport	ISO	J:164563
Biological Process	GO:0015723	bilirubin transport	ISO	J:155856
Biological Process	GO:0015722	canalicular bile acid transport	ISO	J:155856
Biological Process	GO:0050787	detoxification of mercury ion	ISO	J:155856
Biological Process	GO:0030644	intracellular chloride ion homeostasis	ISO	J:155856
Biological Process	GO:0071716	leukotriene transport	ISO	J:155856
Biological Process	GO:0071716	leukotriene transport	ISO	J:164563
Biological Process	GO:0015694	mercury ion transport	ISO	J:155856
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:155856
Biological Process	GO:0015711	organic anion transport	ISO	J:155856
Biological Process	GO:0015732	prostaglandin transport	ISO	J:155856
Biological Process	GO:0043627	response to estrogen	ISO	J:155856
Biological Process	GO:0009410	response to xenobiotic stimulus	ISO	J:155856
Biological Process	GO:0070327	thyroid hormone transport	ISO	J:155856
Biological Process	GO:0070633	transepithelial transport	ISO	J:155856
Biological Process	GO:0055085	transmembrane transport	IBA	J:265628
Biological Process	GO:0042178	xenobiotic catabolic process	ISO	J:155856
Biological Process	GO:1990961	xenobiotic detoxification by transmembrane export across the plasma membrane	ISO	J:155856
Biological Process	GO:0046618	xenobiotic export from cell	ISO	J:164563
Biological Process	GO:0006855	xenobiotic transmembrane transport	ISO	J:164563
Biological Process	GO:0006855	xenobiotic transmembrane transport	ISO	J:155856
Biological Process	GO:1990962	xenobiotic transport across blood-brain barrier	ISO	J:155856