GO Annotations Graph

• Symbol: Nr2f2
• Name: nuclear receptor subfamily 2, group F, member 2
• ID: MGI:1352452

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IDA	J:111670
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004879	nuclear receptor activity	ISO	J:164563
Molecular Function	GO:0004879	nuclear receptor activity	IBA	J:265628
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0001972	retinoic acid binding	ISO	J:164563
Molecular Function	GO:0001972	retinoic acid binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:22384
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:212720
Cellular Component	GO:0005634	nucleus	IDA	J:154112
Cellular Component	GO:0005634	nucleus	IDA	J:94458
Cellular Component	GO:0005634	nucleus	IDA	J:94458
Biological Process	GO:0048856	anatomical structure development	IBA	J:265628
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:98520
Biological Process	GO:0048514	blood vessel morphogenesis	IMP	J:98247
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0008585	female gonad development	ISO	J:164563
Biological Process	GO:0009566	fertilization	IMP	J:120852
Biological Process	GO:0009566	fertilization	IMP	J:120852
Biological Process	GO:0030900	forebrain development	IDA	J:94458
Biological Process	GO:0001701	in utero embryonic development	IMP	J:120852
Biological Process	GO:0001701	in utero embryonic development	IMP	J:120852
Biological Process	GO:1904936	interneuron migration	IDA	J:94458
Biological Process	GO:0001945	lymph vessel development	IEP	J:146844
Biological Process	GO:0060838	lymphatic endothelial cell fate commitment	ISO	J:164563
Biological Process	GO:0001893	maternal placenta development	IMP	J:120852
Biological Process	GO:0001893	maternal placenta development	IMP	J:120852
Biological Process	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0010596	negative regulation of endothelial cell migration	ISO	J:164563
Biological Process	GO:0001937	negative regulation of endothelial cell proliferation	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:22384
Biological Process	GO:0001764	neuron migration	IDA	J:94458
Biological Process	GO:0060674	placenta blood vessel development	IMP	J:120852
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0003084	positive regulation of systemic arterial blood pressure	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0009956	radial pattern formation	IMP	J:98520
Biological Process	GO:0009956	radial pattern formation	IMP	J:98520
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:154112
Biological Process	GO:0007519	skeletal muscle tissue development	IMP	J:103437
Biological Process	GO:0060707	trophoblast giant cell differentiation	IMP	J:120852