Nr4a1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Nr4a1
nuclear receptor subfamily 4, group A, member 1
MGI:1352454

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IDA	J:155191
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:155856
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:40025
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IEA	J:72247
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	IPI	J:136893
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0035259	nuclear glucocorticoid receptor binding	ISO	J:155856
Molecular Function	GO:0035259	nuclear glucocorticoid receptor binding	IBA	J:265628
Molecular Function	GO:0004879	nuclear receptor activity	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:247470
Molecular Function	GO:0005515	protein binding	IPI	J:222151
Molecular Function	GO:0005515	protein binding	IPI	J:91558
Molecular Function	GO:0005515	protein binding	IPI	J:91558
Molecular Function	GO:0005515	protein binding	IPI	J:98743
Molecular Function	GO:0005515	protein binding	IPI	J:37081
Molecular Function	GO:0005515	protein binding	IPI	J:222687
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:155856
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:136893
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:37081
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IEA	J:60000
Cellular Component	GO:0031965	nuclear membrane	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:155191
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:124324
Cellular Component	GO:0005634	nucleus	IDA	J:84428
Cellular Component	GO:0005667	transcription regulator complex	IBA	J:265628
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:40025
Biological Process	GO:0006915	apoptotic process	IMP	J:124324
Biological Process	GO:0002042	cell migration involved in sprouting angiogenesis	ISO	J:164563
Biological Process	GO:0071376	cellular response to corticotropin-releasing hormone stimulus	IDA	J:222687
Biological Process	GO:0071376	cellular response to corticotropin-releasing hormone stimulus	IBA	J:265628
Biological Process	GO:0044344	cellular response to fibroblast growth factor stimulus	ISO	J:164563
Biological Process	GO:0071310	cellular response to organic substance	IDA	J:170688
Biological Process	GO:0035924	cellular response to vascular endothelial growth factor stimulus	ISO	J:164563
Biological Process	GO:0035767	endothelial cell chemotaxis	ISO	J:164563
Biological Process	GO:0045444	fat cell differentiation	IDA	J:222681
Biological Process	GO:0045786	negative regulation of cell cycle	IDA	J:222681
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	IDA	J:84428
Biological Process	GO:0014860	neurotransmitter secretion involved in regulation of skeletal muscle contraction	ISO	J:155856
Biological Process	GO:0043065	positive regulation of apoptotic process	IDA	J:87073
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:37081
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:87073
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:98743
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:91558
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:40025
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:91558
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:73065
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:256173
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:37081
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:91558
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:98743
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0061469	regulation of type B pancreatic cell proliferation	ISO	J:155856
Biological Process	GO:0001975	response to amphetamine	ISO	J:155856
Biological Process	GO:0010035	response to inorganic substance	ISO	J:33283
Biological Process	GO:0035914	skeletal muscle cell differentiation	IMP	J:178918
Biological Process	GO:0006366	transcription by RNA polymerase II	IGI	J:91558
Biological Process	GO:0006366	transcription by RNA polymerase II	IGI	J:91558

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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