Nr1h3 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Nr1h3
nuclear receptor subfamily 1, group H, member 3
MGI:1352462

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031490	chromatin DNA binding	IMP	J:264834
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:210948
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:89079
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004879	nuclear receptor activity	IDA	J:154828
Molecular Function	GO:0004879	nuclear receptor activity	ISO	J:164563
Molecular Function	GO:0004879	nuclear receptor activity	IBA	J:265628
Molecular Function	GO:0004879	nuclear receptor activity	IDA	J:89079
Molecular Function	GO:0046965	nuclear retinoid X receptor binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:226000
Molecular Function	GO:0005515	protein binding	IPI	J:134888
Molecular Function	GO:0005515	protein binding	IPI	J:142045
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:210948
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:94492
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:89079
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0032810	sterol response element binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:154828
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:235724
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IMP	J:235724
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:89079
Cellular Component	GO:0043235	receptor complex	ISO	J:164563
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ISO	J:164563
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	EXP	J:320338
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	IDA	J:154828
Biological Process	GO:0043277	apoptotic cell clearance	ISO	J:164563
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0044255	cellular lipid metabolic process	IDA	J:89079
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IDA	J:173138
Biological Process	GO:0071222	cellular response to lipopolysaccharide	ISO	J:164563
Biological Process	GO:0042632	cholesterol homeostasis	ISO	J:164563
Biological Process	GO:0042632	cholesterol homeostasis	IGI	J:123957
Biological Process	GO:0042632	cholesterol homeostasis	IMP	J:206917
Biological Process	GO:0006351	DNA-templated transcription	IDA	J:89079
Biological Process	GO:0006633	fatty acid biosynthetic process	TAS	J:65994
Biological Process	GO:0009755	hormone-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0055088	lipid homeostasis	IMP	J:142844
Biological Process	GO:0055088	lipid homeostasis	IGI	J:123957
Biological Process	GO:0006629	lipid metabolic process	IEA	J:72247
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0010887	negative regulation of cholesterol storage	IGI	J:123957
Biological Process	GO:0010887	negative regulation of cholesterol storage	ISO	J:164563
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	IGI	J:262347
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:85276
Biological Process	GO:0050728	negative regulation of inflammatory response	IDA	J:173138
Biological Process	GO:0050728	negative regulation of inflammatory response	IBA	J:265628
Biological Process	GO:0032369	negative regulation of lipid transport	ISO	J:164563
Biological Process	GO:0043031	negative regulation of macrophage activation	IDA	J:173138
Biological Process	GO:0090188	negative regulation of pancreatic juice secretion	IMP	J:142844
Biological Process	GO:0048550	negative regulation of pinocytosis	ISO	J:164563
Biological Process	GO:0045861	negative regulation of proteolysis	IMP	J:142844
Biological Process	GO:1903573	negative regulation of response to endoplasmic reticulum stress	IDA	J:206173
Biological Process	GO:0090341	negative regulation of secretion of lysosomal enzymes	IMP	J:142844
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:173138
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0036151	phosphatidylcholine acyl-chain remodeling	IMP	J:206173
Biological Process	GO:0010875	positive regulation of cholesterol efflux	ISO	J:164563
Biological Process	GO:0010875	positive regulation of cholesterol efflux	IDA	J:135705
Biological Process	GO:0032376	positive regulation of cholesterol transport	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:65994
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045723	positive regulation of fatty acid biosynthetic process	ISO	J:164563
Biological Process	GO:0046889	positive regulation of lipid biosynthetic process	ISO	J:164563
Biological Process	GO:0051006	positive regulation of lipoprotein lipase activity	ISO	J:164563
Biological Process	GO:0051247	positive regulation of protein metabolic process	ISO	J:164563
Biological Process	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:154828
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:135705
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:210948
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:154834
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0010867	positive regulation of triglyceride biosynthetic process	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:89079
Biological Process	GO:0032570	response to progesterone	ISO	J:164563
Biological Process	GO:0055092	sterol homeostasis	IMP	J:105722
Biological Process	GO:0070328	triglyceride homeostasis	IMP	J:105722
Biological Process	GO:0070328	triglyceride homeostasis	IGI	J:123957

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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