GO Annotations Graph

• Symbol: Fscn1
• Name: fascin actin-bundling protein 1
• ID: MGI:1352745

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	ISO	J:155856
Molecular Function	GO:0003779	actin binding	ISO	J:164563
Molecular Function	GO:0051015	actin filament binding	ISO	J:164563
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0051015	actin filament binding	ISO	J:128283
Molecular Function	GO:0051015	actin filament binding	IMP	J:128283
Molecular Function	GO:0005515	protein binding	IPI	J:245296
Molecular Function	GO:0005515	protein binding	IPI	J:196252
Molecular Function	GO:0005515	protein binding	IPI	J:214682
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	IEA	J:72247
Cellular Component	GO:0015629	actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0015629	actin cytoskeleton	IBA	J:265628
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0031253	cell projection membrane	ISO	J:164563
Cellular Component	GO:0031253	cell projection membrane	IBA	J:265628
Cellular Component	GO:0005911	cell-cell junction	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0030175	filopodium	ISO	J:155856
Cellular Component	GO:0030175	filopodium	ISO	J:164563
Cellular Component	GO:0030175	filopodium	IDA	J:214682
Cellular Component	GO:0030175	filopodium	IBA	J:265628
Cellular Component	GO:0030175	filopodium	IDA	J:91946
Cellular Component	GO:0030175	filopodium	IDA	J:128283
Cellular Component	GO:0030426	growth cone	IDA	J:214682
Cellular Component	GO:0030426	growth cone	ISO	J:155856
Cellular Component	GO:0030426	growth cone	IBA	J:265628
Cellular Component	GO:0030027	lamellipodium	ISO	J:155856
Cellular Component	GO:0030027	lamellipodium	IDA	J:214682
Cellular Component	GO:0030027	lamellipodium	IBA	J:265628
Cellular Component	GO:0044393	microspike	ISO	J:164563
Cellular Component	GO:0005902	microvillus	ISO	J:155856
Cellular Component	GO:0005902	microvillus	ISO	J:164563
Cellular Component	GO:0005902	microvillus	IBA	J:265628
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0002102	podosome	ISO	J:164563
Cellular Component	GO:0001726	ruffle	ISO	J:155856
Cellular Component	GO:0001726	ruffle	ISO	J:164563
Cellular Component	GO:0001726	ruffle	IBA	J:265628
Cellular Component	GO:0001725	stress fiber	ISO	J:164563
Cellular Component	GO:0001725	stress fiber	ISO	J:155856
Biological Process	GO:0030036	actin cytoskeleton organization	ISO	J:164563
Biological Process	GO:0051017	actin filament bundle assembly	ISO	J:164563
Biological Process	GO:0051017	actin filament bundle assembly	ISO	J:155856
Biological Process	GO:0051017	actin filament bundle assembly	IBA	J:265628
Biological Process	GO:0051017	actin filament bundle assembly	IDA	J:25101
Biological Process	GO:0051017	actin filament bundle assembly	IDA	J:128283
Biological Process	GO:0007015	actin filament organization	IEA	J:72247
Biological Process	GO:0016477	cell migration	IMP	J:168387
Biological Process	GO:0016477	cell migration	ISO	J:164563
Biological Process	GO:0016477	cell migration	IBA	J:265628
Biological Process	GO:0048870	cell motility	ISO	J:164563
Biological Process	GO:0007043	cell-cell junction assembly	ISO	J:164563
Biological Process	GO:0035089	establishment of apical/basal cell polarity	ISO	J:164563
Biological Process	GO:0007163	establishment or maintenance of cell polarity	IBA	J:265628
Biological Process	GO:0030035	microspike assembly	ISO	J:164563
Biological Process	GO:0030046	parallel actin filament bundle assembly	ISO	J:164563
Biological Process	GO:0090091	positive regulation of extracellular matrix disassembly	ISO	J:164563
Biological Process	GO:0051491	positive regulation of filopodium assembly	ISO	J:164563
Biological Process	GO:0051491	positive regulation of filopodium assembly	IMP	J:276418
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	ISO	J:164563
Biological Process	GO:0071803	positive regulation of podosome assembly	ISO	J:164563
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	ISO	J:164563
Biological Process	GO:0032534	regulation of microvillus assembly	ISO	J:164563