GO Annotations Graph

• Symbol: Plcl2
• Name: phospholipase C-like 2
• ID: MGI:1352756

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0050811	GABA receptor binding	ISO	J:116460
Molecular Function	GO:0070679	inositol 1,4,5 trisphosphate binding	IEA	J:72247
Molecular Function	GO:0004435	phosphatidylinositol phospholipase C activity	IEA	J:72247
Molecular Function	GO:0008081	phosphoric diester hydrolase activity	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Biological Process	GO:0002322	B cell proliferation involved in immune response	IMP	J:85960
Biological Process	GO:0002337	B-1a B cell differentiation	IMP	J:85960
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	IGI	J:116460
Biological Process	GO:0035556	intracellular signal transduction	IEA	J:72247
Biological Process	GO:0006629	lipid metabolic process	IEA	J:72247
Biological Process	GO:0050859	negative regulation of B cell receptor signaling pathway	IMP	J:85960
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	IGI	J:231034
Biological Process	GO:1900122	positive regulation of receptor binding	IGI	J:116460
Biological Process	GO:0032228	regulation of synaptic transmission, GABAergic	IGI	J:116460
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0007165	signal transduction	IEA	J:72247