GO Annotations Graph

• Symbol: Aldh1a1
• Name: aldehyde dehydrogenase family 1, subfamily A1
• ID: MGI:1353450

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0033737	1-pyrroline dehydrogenase activity	IEA	J:72245
Molecular Function	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity	IDA	J:82902
Molecular Function	GO:0106373	3-deoxyglucosone dehydrogenase activity	ISO	J:164563
Molecular Function	GO:0004029	aldehyde dehydrogenase (NAD+) activity	ISO	J:155856
Molecular Function	GO:0004029	aldehyde dehydrogenase (NAD+) activity	ISO	J:164563
Molecular Function	GO:0004029	aldehyde dehydrogenase (NAD+) activity	ISO	J:322155
Molecular Function	GO:0019145	aminobutyraldehyde dehydrogenase activity	IMP	J:226538
Molecular Function	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity	ISO	J:155856
Molecular Function	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity	IBA	J:265628
Molecular Function	GO:0043878	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity	IEA	J:72245
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0051287	NAD binding	ISS	J:240299
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:72247
Molecular Function	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	IEA	J:72247
Molecular Function	GO:0001758	retinal dehydrogenase activity	ISO	J:155856
Cellular Component	GO:0030424	axon	IDA	J:226538
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0045202	synapse	IDA	J:226538
Biological Process	GO:0042904	9-cis-retinoic acid biosynthetic process	IDA	J:83534
Biological Process	GO:0042905	9-cis-retinoic acid metabolic process	ISO	J:155856
Biological Process	GO:0006915	apoptotic process	IGI	J:102847
Biological Process	GO:0006915	apoptotic process	IGI	J:108515
Biological Process	GO:0110095	cellular detoxification of aldehyde	ISO	J:164563
Biological Process	GO:0110095	cellular detoxification of aldehyde	ISO	J:155856
Biological Process	GO:0048048	embryonic eye morphogenesis	IGI	J:108515
Biological Process	GO:0048048	embryonic eye morphogenesis	IGI	J:102847
Biological Process	GO:0030392	fructosamine catabolic process	ISO	J:164563
Biological Process	GO:0006001	fructose catabolic process	IDA	J:322167
Biological Process	GO:0006001	fructose catabolic process	IDA	J:322154
Biological Process	GO:0009449	gamma-aminobutyric acid biosynthetic process	IMP	J:226538
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0036438	maintenance of lens transparency	ISO	J:155856
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	IMP	J:187531
Biological Process	GO:0002072	optic cup morphogenesis involved in camera-type eye development	IGI	J:108515
Biological Process	GO:0043065	positive regulation of apoptotic process	IGI	J:108515
Biological Process	GO:0043065	positive regulation of apoptotic process	IGI	J:102847
Biological Process	GO:0045471	response to ethanol	ISO	J:155856
Biological Process	GO:0006979	response to oxidative stress	ISO	J:155856
Biological Process	GO:0009410	response to xenobiotic stimulus	IDA	J:145577
Biological Process	GO:0002138	retinoic acid biosynthetic process	ISO	J:155856
Biological Process	GO:0042573	retinoic acid metabolic process	IGI	J:102847
Biological Process	GO:0042573	retinoic acid metabolic process	IMP	J:83957
Biological Process	GO:0042573	retinoic acid metabolic process	IMP	J:85538
Biological Process	GO:0042573	retinoic acid metabolic process	IGI	J:102847
Biological Process	GO:0042573	retinoic acid metabolic process	IDA	J:54527
Biological Process	GO:0042573	retinoic acid metabolic process	IMP	J:102847
Biological Process	GO:0042573	retinoic acid metabolic process	IGI	J:102847
Biological Process	GO:0001523	retinoid metabolic process	ISO	J:155856
Biological Process	GO:0042572	retinol metabolic process	IMP	J:85538