GO Annotations Graph

• Symbol: Mlh3
• Name: mutL homolog 3
• ID: MGI:1353455

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016887	ATP hydrolysis activity	IBA	J:265628
Molecular Function	GO:0019237	centromeric DNA binding	IDA	J:104493
Molecular Function	GO:0003682	chromatin binding	IDA	J:78200
Cellular Component	GO:0005712	chiasma	IDA	J:78200
Cellular Component	GO:0005712	chiasma	IDA	J:123677
Cellular Component	GO:0000793	condensed chromosome	IDA	J:78200
Cellular Component	GO:0000794	condensed nuclear chromosome	IDA	J:215796
Cellular Component	GO:0001673	male germ cell nucleus	IDA	J:123677
Cellular Component	GO:0032300	mismatch repair complex	IBA	J:265628
Cellular Component	GO:0032300	mismatch repair complex	IDA	J:182264
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912487
Cellular Component	GO:0000795	synaptonemal complex	IDA	J:104493
Cellular Component	GO:0000795	synaptonemal complex	IDA	J:93127
Biological Process	GO:0006974	DNA damage response	IGI	J:102704
Biological Process	GO:0006974	DNA damage response	IMP	J:102704
Biological Process	GO:0007144	female meiosis I	IMP	J:78200
Biological Process	GO:0007140	male meiotic nuclear division	IMP	J:78200
Biological Process	GO:0007140	male meiotic nuclear division	IMP	J:93127
Biological Process	GO:0006298	mismatch repair	IBA	J:265628
Biological Process	GO:0006298	mismatch repair	IGI	J:102704
Biological Process	GO:0006298	mismatch repair	IMP	J:102704
Biological Process	GO:0008104	protein localization	IMP	J:104493
Biological Process	GO:0007130	synaptonemal complex assembly	IMP	J:104493