GO Annotations Graph

• Symbol: Slc25a5
• Name: solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
• ID: MGI:1353496

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0000295	adenine nucleotide transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015297	antiporter activity	IEA	J:60000
Molecular Function	GO:0005471	ATP:ADP antiporter activity	IMP	J:287489
Molecular Function	GO:0005471	ATP:ADP antiporter activity	IDA	J:288657
Molecular Function	GO:0017077	oxidative phosphorylation uncoupler activity	IDA	J:288657
Molecular Function	GO:0005515	protein binding	IPI	J:287489
Molecular Function	GO:0015078	proton transmembrane transporter activity	IDA	J:288657
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0005743	mitochondrial inner membrane	ISO	J:155856
Cellular Component	GO:0005743	mitochondrial inner membrane	IDA	J:242350
Cellular Component	GO:0005743	mitochondrial inner membrane	HDA	J:100953
Cellular Component	GO:0042645	mitochondrial nucleoid	ISO	J:164563
Cellular Component	GO:0005757	mitochondrial permeability transition pore complex	IMP	J:287067
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0071817	MMXD complex	ISO	J:164563
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Biological Process	GO:1990845	adaptive thermogenesis	IMP	J:288657
Biological Process	GO:0051503	adenine nucleotide transport	ISO	J:164563
Biological Process	GO:0030183	B cell differentiation	IMP	J:234617
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IEP	J:163558
Biological Process	GO:0007059	chromosome segregation	IEA	J:60000
Biological Process	GO:0030218	erythrocyte differentiation	IMP	J:234617
Biological Process	GO:0140021	mitochondrial ADP transmembrane transport	IDA	J:288657
Biological Process	GO:0140021	mitochondrial ADP transmembrane transport	IMP	J:287489
Biological Process	GO:1990544	mitochondrial ATP transmembrane transport	IMP	J:287489
Biological Process	GO:1990544	mitochondrial ATP transmembrane transport	IDA	J:288657
Biological Process	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	IBA	J:265628
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:1901526	positive regulation of mitophagy	IDA	J:287489
Biological Process	GO:0046902	regulation of mitochondrial membrane permeability	IMP	J:287067
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247