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GO Annotations Graph
Symbol
Name
ID
Pik3cg
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
MGI:1353576

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:00163031-phosphatidylinositol-3-kinase activityIDAJ:65490
Molecular FunctionGO:00163031-phosphatidylinositol-3-kinase activityISOJ:164563
Molecular FunctionGO:00163031-phosphatidylinositol-3-kinase activityISOJ:155856
Molecular FunctionGO:00163031-phosphatidylinositol-3-kinase activityIBAJ:265628
Molecular FunctionGO:00350051-phosphatidylinositol-4-phosphate 3-kinase activityISOJ:164563
Molecular FunctionGO:00350051-phosphatidylinositol-4-phosphate 3-kinase activityIBAJ:265628
Molecular FunctionGO:0005524ATP bindingIEAJ:60000
Molecular FunctionGO:0046875ephrin receptor bindingISOJ:164563
Molecular FunctionGO:0042802identical protein bindingISOJ:164563
Molecular FunctionGO:0016301kinase activityISOJ:217701
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0052812phosphatidylinositol-3,4-bisphosphate 5-kinase activityIEAJ:72245
Molecular FunctionGO:0046934phosphatidylinositol-4,5-bisphosphate 3-kinase activityISOJ:164563
Molecular FunctionGO:0005515protein bindingIPIJ:173562
Molecular FunctionGO:0005515protein bindingIPIJ:97091
Molecular FunctionGO:0005515protein bindingIPIJ:201418
Molecular FunctionGO:0106310protein serine kinase activityISOJ:164563
Molecular FunctionGO:0004674protein serine/threonine kinase activityIEAJ:72245
Molecular FunctionGO:0004674protein serine/threonine kinase activityIEAJ:60000
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0005737cytoplasmIBAJ:265628
Cellular ComponentGO:0005829cytosolISOJ:164563
Cellular ComponentGO:0005829cytosolTASReactome:R-MMU-9027268
Cellular ComponentGO:0005829cytosolTASReactome:R-MMU-9680646
Cellular ComponentGO:0005829cytosolTASReactome:R-MMU-9682158
Cellular ComponentGO:0005829cytosolTASReactome:R-MMU-9682182
Cellular ComponentGO:0016020membraneISOJ:164563
Cellular ComponentGO:0005942phosphatidylinositol 3-kinase complexISOJ:155856
Cellular ComponentGO:0005943phosphatidylinositol 3-kinase complex, class IAISOJ:164563
Cellular ComponentGO:0005943phosphatidylinositol 3-kinase complex, class IAIBAJ:265628
Cellular ComponentGO:0005944phosphatidylinositol 3-kinase complex, class IBISOJ:164563
Cellular ComponentGO:0005944phosphatidylinositol 3-kinase complex, class IBIBAJ:265628
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Cellular ComponentGO:0005886plasma membraneIBAJ:265628
Biological ProcessGO:0001525angiogenesisIEAJ:60000
Biological ProcessGO:0016477cell migrationIBAJ:265628
Biological ProcessGO:0071320cellular response to cAMPIMPJ:210072
Biological ProcessGO:0006935chemotaxisIEAJ:60000
Biological ProcessGO:0006897endocytosisIEAJ:60000
Biological ProcessGO:0007186G protein-coupled receptor signaling pathwayISOJ:164563
Biological ProcessGO:0097284hepatocyte apoptotic processISOJ:155856
Biological ProcessGO:0002376immune system processIEAJ:60000
Biological ProcessGO:0006954inflammatory responseIEAJ:60000
Biological ProcessGO:0006629lipid metabolic processIEAJ:60000
Biological ProcessGO:2000270negative regulation of fibroblast apoptotic processIDAJ:91529
Biological ProcessGO:0010897negative regulation of triglyceride catabolic processISOJ:155856
Biological ProcessGO:0014065phosphatidylinositol 3-kinase signalingISOJ:164563
Biological ProcessGO:0014065phosphatidylinositol 3-kinase signalingIMPJ:161894
Biological ProcessGO:0014065phosphatidylinositol 3-kinase signalingIBAJ:265628
Biological ProcessGO:0046854phosphatidylinositol phosphate biosynthetic processISOJ:164563
Biological ProcessGO:0046854phosphatidylinositol phosphate biosynthetic processISOJ:155856
Biological ProcessGO:0036092phosphatidylinositol-3-phosphate biosynthetic processIBAJ:265628
Biological ProcessGO:0048015phosphatidylinositol-mediated signalingIEAJ:72247
Biological ProcessGO:0016310phosphorylationISOJ:217701
Biological ProcessGO:0002675positive regulation of acute inflammatory responseISOJ:155856
Biological ProcessGO:0043085positive regulation of catalytic activityIMPJ:210072
Biological ProcessGO:0007204positive regulation of cytosolic calcium ion concentrationISOJ:155856
Biological ProcessGO:0010595positive regulation of endothelial cell migrationISOJ:164563
Biological ProcessGO:0010595positive regulation of endothelial cell migrationIMPJ:161894
Biological ProcessGO:0043406positive regulation of MAP kinase activityISOJ:164563
Biological ProcessGO:0051897positive regulation of protein kinase B signalingISOJ:164563
Biological ProcessGO:0035022positive regulation of Rac protein signal transductionIMPJ:161894
Biological ProcessGO:0035022positive regulation of Rac protein signal transductionISOJ:164563
Biological ProcessGO:0006468protein phosphorylationIDAJ:91529
Biological ProcessGO:0045765regulation of angiogenesisISOJ:164563
Biological ProcessGO:1903169regulation of calcium ion transmembrane transportIMPJ:210072
Biological ProcessGO:0001932regulation of protein phosphorylationIMPJ:210072
Biological ProcessGO:0032252secretory granule localizationISOJ:155856
Biological ProcessGO:0003376sphingosine-1-phosphate receptor signaling pathwayIMPJ:161894
Biological ProcessGO:0003376sphingosine-1-phosphate receptor signaling pathwayISOJ:164563

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory