GO Annotations Graph

• Symbol: Cbx8
• Name: chromobox 8
• ID: MGI:1353589

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IBA	J:265628
Molecular Function	GO:0035064	methylated histone binding	ISO	J:164563
Molecular Function	GO:0035064	methylated histone binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:122905
Molecular Function	GO:0005515	protein binding	IPI	J:104662
Molecular Function	GO:0005515	protein binding	IPI	J:104662
Molecular Function	GO:0005515	protein binding	IPI	J:104662
Molecular Function	GO:0003727	single-stranded RNA binding	IDA	J:106925
Molecular Function	GO:0097027	ubiquitin-protein transferase activator activity	IDA	J:104662
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0000785	chromatin	IBA	J:265628
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000792	heterochromatin	IDA	J:106925
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:106925
Cellular Component	GO:0005634	nucleus	IDA	J:154112
Cellular Component	GO:0005634	nucleus	ISS	J:60239
Cellular Component	GO:0031519	PcG protein complex	ISO	J:164563
Cellular Component	GO:0035102	PRC1 complex	ISO	J:164563
Cellular Component	GO:0035102	PRC1 complex	IBA	J:265628
Cellular Component	GO:0035102	PRC1 complex	IDA	J:104662
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0031507	heterochromatin formation	ISS	J:60239
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0032967	positive regulation of collagen biosynthetic process	ISO	J:155856
Biological Process	GO:0045739	positive regulation of DNA repair	ISO	J:155856