GO Annotations Graph

• Symbol: Hacd1
• Name: 3-hydroxyacyl-CoA dehydratase 1
• ID: MGI:1353592

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0080023	(3R)-3-hydroxyacyl-CoA dehydratase activity	ISO	J:164563
Molecular Function	GO:0018812	3-hydroxyacyl-CoA dehydratase activity	IBA	J:265628
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0046848	hydroxyapatite binding	ISO	J:164563
Molecular Function	GO:0016829	lyase activity	IEA	J:60000
Molecular Function	GO:0102158	very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Biological Process	GO:0071529	cementum mineralization	ISO	J:164563
Biological Process	GO:0006633	fatty acid biosynthetic process	IEA	J:60000
Biological Process	GO:0030497	fatty acid elongation	ISO	J:164563
Biological Process	GO:0030497	fatty acid elongation	IBA	J:265628
Biological Process	GO:0006631	fatty acid metabolic process	IEA	J:60000
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0014902	myotube differentiation	IGI	J:183657
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	ISO	J:164563
Biological Process	GO:0065003	protein-containing complex assembly	ISO	J:164563
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	IMP	J:183657
Biological Process	GO:0010389	regulation of G2/M transition of mitotic cell cycle	IMP	J:183657
Biological Process	GO:0030148	sphingolipid biosynthetic process	ISO	J:164563
Biological Process	GO:0030148	sphingolipid biosynthetic process	IBA	J:265628
Biological Process	GO:0042761	very long-chain fatty acid biosynthetic process	ISO	J:164563
Biological Process	GO:0042761	very long-chain fatty acid biosynthetic process	IBA	J:265628