GO Annotations Graph

• Symbol: Angptl3
• Name: angiopoietin-like 3
• ID: MGI:1353627

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004857	enzyme inhibitor activity	IDA	J:78948
Molecular Function	GO:0008083	growth factor activity	ISO	J:164563
Molecular Function	GO:0008201	heparin binding	IEA	J:60000
Molecular Function	GO:0005178	integrin binding	ISO	J:164563
Molecular Function	GO:0004859	phospholipase inhibitor activity	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IDA	J:203527
Cellular Component	GO:0062023	collagen-containing extracellular matrix	IBA	J:265628
Cellular Component	GO:0005769	early endosome	IDA	J:203527
Cellular Component	GO:0005576	extracellular region	ISS	J:60238
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:203527
Biological Process	GO:0055090	acylglycerol homeostasis	IMP	J:131463
Biological Process	GO:0055090	acylglycerol homeostasis	ISO	J:164563
Biological Process	GO:0001525	angiogenesis	IEA	J:60000
Biological Process	GO:0048844	artery morphogenesis	IMP	J:84022
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0007160	cell-matrix adhesion	ISO	J:164563
Biological Process	GO:0042632	cholesterol homeostasis	IMP	J:131463
Biological Process	GO:0042632	cholesterol homeostasis	ISO	J:164563
Biological Process	GO:0042632	cholesterol homeostasis	IBA	J:265628
Biological Process	GO:0008203	cholesterol metabolic process	ISO	J:164563
Biological Process	GO:0006631	fatty acid metabolic process	ISO	J:164563
Biological Process	GO:0006071	glycerol metabolic process	ISO	J:164563
Biological Process	GO:0055088	lipid homeostasis	ISO	J:164563
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0019915	lipid storage	ISO	J:164563
Biological Process	GO:0051005	negative regulation of lipoprotein lipase activity	ISO	J:164563
Biological Process	GO:0010519	negative regulation of phospholipase activity	ISO	J:164563
Biological Process	GO:0010519	negative regulation of phospholipase activity	IMP	J:131463
Biological Process	GO:0010519	negative regulation of phospholipase activity	IBA	J:265628
Biological Process	GO:0009395	phospholipid catabolic process	ISO	J:164563
Biological Process	GO:0009395	phospholipid catabolic process	IBA	J:265628
Biological Process	GO:0055091	phospholipid homeostasis	ISO	J:164563
Biological Process	GO:0055091	phospholipid homeostasis	IMP	J:131463
Biological Process	GO:0055091	phospholipid homeostasis	IBA	J:265628
Biological Process	GO:0006644	phospholipid metabolic process	ISO	J:164563
Biological Process	GO:0045766	positive regulation of angiogenesis	ISO	J:164563
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0050996	positive regulation of lipid catabolic process	ISO	J:164563
Biological Process	GO:0045834	positive regulation of lipid metabolic process	NAS	J:75358
Biological Process	GO:0007165	signal transduction	ISO	J:164563
Biological Process	GO:0070328	triglyceride homeostasis	IMP	J:155061
Biological Process	GO:0070328	triglyceride homeostasis	IBA	J:265628
Biological Process	GO:0070328	triglyceride homeostasis	ISO	J:73065
Biological Process	GO:0006641	triglyceride metabolic process	NAS	J:78948