GO Annotations Graph

• Symbol: Ercc4
• Name: excision repair cross-complementing rodent repair deficiency, complementation group 4
• ID: MGI:1354163

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity	ISO	J:164563
Molecular Function	GO:0003684	damaged DNA binding	ISO	J:164563
Molecular Function	GO:0003684	damaged DNA binding	IBA	J:265628
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0004520	DNA endonuclease activity	ISO	J:164563
Molecular Function	GO:0004520	DNA endonuclease activity	ISO	J:164563
Molecular Function	GO:0004519	endonuclease activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0004518	nuclease activity	IEA	J:60000
Molecular Function	GO:0004518	nuclease activity	IEA	J:72247
Molecular Function	GO:1990841	promoter-specific chromatin binding	IDA	J:181994
Molecular Function	GO:0003697	single-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0003697	single-stranded DNA binding	IBA	J:265628
Molecular Function	GO:0000014	single-stranded DNA endodeoxyribonuclease activity	IBA	J:265628
Molecular Function	GO:0001094	TFIID-class transcription factor complex binding	IDA	J:181994
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000781	chromosome, telomeric region	ISO	J:164563
Cellular Component	GO:0070522	ERCC4-ERCC1 complex	ISO	J:164563
Cellular Component	GO:0000109	nucleotide-excision repair complex	ISO	J:60251
Cellular Component	GO:0000110	nucleotide-excision repair factor 1 complex	ISO	J:164563
Cellular Component	GO:0000110	nucleotide-excision repair factor 1 complex	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0034644	cellular response to UV	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006281	DNA repair	ISO	J:164563
Biological Process	GO:0006281	DNA repair	IMP	J:87684
Biological Process	GO:0000724	double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:0000724	double-strand break repair via homologous recombination	IBA	J:265628
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	ISO	J:164563
Biological Process	GO:1905768	negative regulation of double-stranded telomeric DNA binding	ISO	J:164563
Biological Process	GO:1905765	negative regulation of protection from non-homologous end joining at telomere	ISO	J:164563
Biological Process	GO:0032205	negative regulation of telomere maintenance	ISO	J:164563
Biological Process	GO:1904357	negative regulation of telomere maintenance via telomere lengthening	ISO	J:164563
Biological Process	GO:0006289	nucleotide-excision repair	ISO	J:164563
Biological Process	GO:0006289	nucleotide-excision repair	ISO	J:60251
Biological Process	GO:1901255	nucleotide-excision repair involved in interstrand cross-link repair	ISO	J:164563
Biological Process	GO:1901255	nucleotide-excision repair involved in interstrand cross-link repair	IBA	J:265628
Biological Process	GO:0010506	regulation of autophagy	IMP	J:136907
Biological Process	GO:0000712	resolution of meiotic recombination intermediates	IBA	J:265628
Biological Process	GO:0009411	response to UV	ISO	J:164563
Biological Process	GO:0000723	telomere maintenance	ISO	J:164563
Biological Process	GO:0061819	telomeric DNA-containing double minutes formation	ISO	J:164563
Biological Process	GO:0009650	UV protection	IMP	J:87684