GO Annotations Graph

• Symbol: Lsm4
• Name: LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
• ID: MGI:1354692

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042731	PH domain binding	ISO	J:164563
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Molecular Function	GO:0017070	U6 snRNA binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISS	J:93906
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0120115	Lsm2-8 complex	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0005654	nucleoplasm	ISS	J:93906
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0000932	P-body	IBA	J:265628
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0005681	spliceosomal complex	ISS	J:59997
Cellular Component	GO:0097526	spliceosomal tri-snRNP complex	IBA	J:265628
Cellular Component	GO:0071005	U2-type precatalytic spliceosome	ISO	J:164563
Cellular Component	GO:0046540	U4/U6 x U5 tri-snRNP complex	ISO	J:164563
Cellular Component	GO:0005688	U6 snRNP	IBA	J:265628
Biological Process	GO:0006397	mRNA processing	IEA	J:60000
Biological Process	GO:0000398	mRNA splicing, via spliceosome	ISO	J:164563
Biological Process	GO:0000956	nuclear-transcribed mRNA catabolic process	IEA	J:72247
Biological Process	GO:0033962	P-body assembly	IBA	J:265628
Biological Process	GO:0006396	RNA processing	IEA	J:72247
Biological Process	GO:0008380	RNA splicing	IEA	J:60000
Biological Process	GO:0000387	spliceosomal snRNP assembly	IBA	J:265628