Symbol Name ID |
Fbxw7
F-box and WD-40 domain protein 7 MGI:1354695 |
Category | GO ID | Classification Term | Evidence | Reference | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Molecular Function | GO:0030332 | cyclin binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0042802 | identical protein binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0050816 | phosphothreonine residue binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:252001 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:204747 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:138546 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:71503 | |||||||||
Molecular Function | GO:0030674 | protein-macromolecule adaptor activity | ISO | J:164563 | |||||||||
Molecular Function | GO:0043130 | ubiquitin binding | IBA | J:265628 | |||||||||
Molecular Function | GO:0061630 | ubiquitin protein ligase activity | TAS | Reactome:R-MMU-9008715 | |||||||||
Molecular Function | GO:0031625 | ubiquitin protein ligase binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0097027 | ubiquitin-protein transferase activator activity | ISO | J:164563 | |||||||||
Cellular Component | GO:0005694 | chromosome | IEA | J:60000 | |||||||||
Cellular Component | GO:0005737 | cytoplasm | ISO | J:164563 | |||||||||
Cellular Component | GO:0005737 | cytoplasm | ISO | J:164563 | |||||||||
Cellular Component | GO:0005737 | cytoplasm | IBA | J:265628 | |||||||||
Cellular Component | GO:0005737 | cytoplasm | TAS | J:71503 | |||||||||
Cellular Component | GO:0005829 | cytosol | TAS | Reactome:R-MMU-9008677 | |||||||||
Cellular Component | GO:0005829 | cytosol | TAS | Reactome:R-MMU-9008715 | |||||||||
Cellular Component | GO:0005829 | cytosol | TAS | Reactome:R-MMU-9008717 | |||||||||
Cellular Component | GO:0005783 | endoplasmic reticulum | IDA | J:73276 | |||||||||
Cellular Component | GO:0005794 | Golgi apparatus | IDA | J:73276 | |||||||||
Cellular Component | GO:0016020 | membrane | NAS | J:204747 | |||||||||
Cellular Component | GO:0005739 | mitochondrion | IDA | J:204747 | |||||||||
Cellular Component | GO:0005730 | nucleolus | ISO | J:164563 | |||||||||
Cellular Component | GO:0005730 | nucleolus | IDA | J:138546 | |||||||||
Cellular Component | GO:0005654 | nucleoplasm | ISO | J:164563 | |||||||||
Cellular Component | GO:0005634 | nucleus | IDA | J:168265 | |||||||||
Cellular Component | GO:0005634 | nucleus | IBA | J:265628 | |||||||||
Cellular Component | GO:0005634 | nucleus | TAS | J:71503 | |||||||||
Cellular Component | GO:0005634 | nucleus | IDA | J:138546 | |||||||||
Cellular Component | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex | ISO | J:164563 | |||||||||
Cellular Component | GO:0048471 | perinuclear region of cytoplasm | IDA | J:168265 | |||||||||
Cellular Component | GO:0032991 | protein-containing complex | ISO | J:164563 | |||||||||
Cellular Component | GO:0019005 | SCF ubiquitin ligase complex | ISO | J:164563 | |||||||||
Cellular Component | GO:0019005 | SCF ubiquitin ligase complex | ISO | J:164563 | |||||||||
Biological Process | GO:0034644 | cellular response to UV | ISO | J:164563 | |||||||||
Biological Process | GO:0006974 | DNA damage response | ISO | J:164563 | |||||||||
Biological Process | GO:0006281 | DNA repair | IEA | J:60000 | |||||||||
Biological Process | GO:0030324 | lung development | IMP | J:172214 | |||||||||
Biological Process | GO:0010629 | negative regulation of gene expression | ISO | J:164563 | |||||||||
Biological Process | GO:2001205 | negative regulation of osteoclast development | IMP | J:251942 | |||||||||
Biological Process | GO:2001205 | negative regulation of osteoclast development | ISO | J:164563 | |||||||||
Biological Process | GO:1903026 | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding | IDA | J:138546 | |||||||||
Biological Process | GO:0007219 | Notch signaling pathway | IDA | J:71503 | |||||||||
Biological Process | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity | ISO | J:164563 | |||||||||
Biological Process | GO:0070374 | positive regulation of ERK1 and ERK2 cascade | ISO | J:164563 | |||||||||
Biological Process | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway | ISO | J:164563 | |||||||||
Biological Process | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway | IMP | J:204747 | |||||||||
Biological Process | GO:1901800 | positive regulation of proteasomal protein catabolic process | ISO | J:164563 | |||||||||
Biological Process | GO:1901800 | positive regulation of proteasomal protein catabolic process | IMP | J:204747 | |||||||||
Biological Process | GO:1903955 | positive regulation of protein targeting to mitochondrion | ISO | J:164563 | |||||||||
Biological Process | GO:0031398 | positive regulation of protein ubiquitination | ISO | J:164563 | |||||||||
Biological Process | GO:2000060 | positive regulation of ubiquitin-dependent protein catabolic process | IMP | J:271692 | |||||||||
Biological Process | GO:2000060 | positive regulation of ubiquitin-dependent protein catabolic process | ISO | J:164563 | |||||||||
Biological Process | GO:0051443 | positive regulation of ubiquitin-protein transferase activity | ISO | J:164563 | |||||||||
Biological Process | GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | ISO | J:164563 | |||||||||
Biological Process | GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | ISO | J:164563 | |||||||||
Biological Process | GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | IBA | J:265628 | |||||||||
Biological Process | GO:0031648 | protein destabilization | IDA | J:138546 | |||||||||
Biological Process | GO:0050821 | protein stabilization | ISO | J:164563 | |||||||||
Biological Process | GO:0016567 | protein ubiquitination | ISO | J:164563 | |||||||||
Biological Process | GO:0016567 | protein ubiquitination | ISO | J:79007 | |||||||||
Biological Process | GO:1903146 | regulation of autophagy of mitochondrion | ISO | J:164563 | |||||||||
Biological Process | GO:0090049 | regulation of cell migration involved in sprouting angiogenesis | IMP | J:219052 | |||||||||
Biological Process | GO:0042752 | regulation of circadian rhythm | IMP | J:271692 | |||||||||
Biological Process | GO:0042752 | regulation of circadian rhythm | ISO | J:164563 | |||||||||
Biological Process | GO:0048511 | rhythmic process | IEA | J:60000 | |||||||||
Biological Process | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | IDA | J:252001 | |||||||||
Biological Process | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | ISO | J:164563 | |||||||||
Biological Process | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | ISO | J:164563 | |||||||||
Biological Process | GO:0007062 | sister chromatid cohesion | ISO | J:164563 | |||||||||
Biological Process | GO:0010992 | ubiquitin recycling | IBA | J:265628 | |||||||||
Biological Process | GO:0001570 | vasculogenesis | IMP | J:172214 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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