GO Annotations Graph

• Symbol: Atp8a2
• Name: ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
• ID: MGI:1354710

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015247	aminophospholipid flippase activity	IMP	J:188127
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0016887	ATP hydrolysis activity	IEA	J:72247
Molecular Function	GO:0140326	ATPase-coupled intramembrane lipid transporter activity	IBA	J:265628
Molecular Function	GO:0000287	magnesium ion binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:72247
Molecular Function	GO:0005215	transporter activity	IEA	J:72247
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005768	endosome	IDA	J:211318
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:211318
Cellular Component	GO:0016020	membrane	IDA	J:188127
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:1990531	phospholipid-translocating ATPase complex	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0007409	axonogenesis	IMP	J:11718
Biological Process	GO:0050908	detection of light stimulus involved in visual perception	IMP	J:211318
Biological Process	GO:0008340	determination of adult lifespan	IMP	J:11718
Biological Process	GO:0042755	eating behavior	IMP	J:11718
Biological Process	GO:0042472	inner ear morphogenesis	IMP	J:211318
Biological Process	GO:0003011	involuntary skeletal muscle contraction	IMP	J:11718
Biological Process	GO:0006869	lipid transport	IEA	J:60000
Biological Process	GO:0060052	neurofilament cytoskeleton organization	IMP	J:188127
Biological Process	GO:0050884	neuromuscular process controlling posture	IMP	J:11718
Biological Process	GO:0048666	neuron development	IBA	J:265628
Biological Process	GO:0048666	neuron development	IMP	J:11718
Biological Process	GO:0031175	neuron projection development	ISO	J:73065
Biological Process	GO:0045332	phospholipid translocation	IBA	J:265628
Biological Process	GO:0015914	phospholipid transport	IEA	J:72247
Biological Process	GO:0040018	positive regulation of multicellular organism growth	IMP	J:11718
Biological Process	GO:0010976	positive regulation of neuron projection development	IDA	J:185526
Biological Process	GO:0061092	positive regulation of phospholipid translocation	IDA	J:188127
Biological Process	GO:0010996	response to auditory stimulus	IMP	J:211318
Biological Process	GO:0010842	retina layer formation	IMP	J:211318
Biological Process	GO:0043588	skin development	IMP	J:11718