GO Annotations Graph

• Symbol: Acsl4
• Name: acyl-CoA synthetase long-chain family member 4
• ID: MGI:1354713

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0047676	arachidonate-CoA ligase activity	ISO	J:164563
Molecular Function	GO:0047676	arachidonate-CoA ligase activity	ISO	J:155856
Molecular Function	GO:0047676	arachidonate-CoA ligase activity	ISO	J:164563
Molecular Function	GO:0047676	arachidonate-CoA ligase activity	IBA	J:265628
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0016874	ligase activity	IEA	J:60000
Molecular Function	GO:0004467	long-chain fatty acid-CoA ligase activity	ISO	J:164563
Molecular Function	GO:0004467	long-chain fatty acid-CoA ligase activity	ISO	J:155856
Molecular Function	GO:0004467	long-chain fatty acid-CoA ligase activity	ISO	J:164563
Molecular Function	GO:0004467	long-chain fatty acid-CoA ligase activity	ISO	J:60348
Molecular Function	GO:0004467	long-chain fatty acid-CoA ligase activity	IDA	J:193737
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0031957	very long-chain fatty acid-CoA ligase activity	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IEA	J:60000
Cellular Component	GO:0005811	lipid droplet	ISO	J:164563
Cellular Component	GO:0005811	lipid droplet	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0044233	mitochondria-associated endoplasmic reticulum membrane	ISO	J:73065
Cellular Component	GO:0031966	mitochondrial membrane	ISO	J:155856
Cellular Component	GO:0005741	mitochondrial outer membrane	IEA	J:60000
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	IDA	J:193737
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005777	peroxisome	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0060996	dendritic spine development	ISO	J:155856
Biological Process	GO:0060136	embryonic process involved in female pregnancy	IMP	J:70023
Biological Process	GO:0006631	fatty acid metabolic process	ISO	J:155856
Biological Process	GO:0015908	fatty acid transport	ISO	J:155856
Biological Process	GO:0008610	lipid biosynthetic process	ISO	J:164563
Biological Process	GO:0006629	lipid metabolic process	ISO	J:164563
Biological Process	GO:0001676	long-chain fatty acid metabolic process	ISO	J:155856
Biological Process	GO:0001676	long-chain fatty acid metabolic process	ISO	J:164563
Biological Process	GO:0001676	long-chain fatty acid metabolic process	IDA	J:193737
Biological Process	GO:0001676	long-chain fatty acid metabolic process	IBA	J:265628
Biological Process	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process	ISO	J:155856
Biological Process	GO:0035336	long-chain fatty-acyl-CoA metabolic process	IBA	J:265628
Biological Process	GO:0032307	negative regulation of prostaglandin secretion	ISO	J:164563
Biological Process	GO:0030182	neuron differentiation	IBA	J:265628
Biological Process	GO:0030307	positive regulation of cell growth	ISO	J:164563
Biological Process	GO:0032024	positive regulation of insulin secretion	ISO	J:155856
Biological Process	GO:0019217	regulation of fatty acid metabolic process	TAS	J:60348
Biological Process	GO:0019432	triglyceride biosynthetic process	ISO	J:155856