GO Annotations Graph

• Symbol: Magi2
• Name: membrane associated guanylate kinase, WW and PDZ domain containing 2
• ID: MGI:1354953

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0070697	activin receptor binding	IPI	J:60559
Molecular Function	GO:0031697	beta-1 adrenergic receptor binding	ISO	J:164563
Molecular Function	GO:0031697	beta-1 adrenergic receptor binding	IBA	J:265628
Molecular Function	GO:0019894	kinesin binding	ISO	J:155856
Molecular Function	GO:0060090	molecular adaptor activity	IEA	J:72247
Molecular Function	GO:0019902	phosphatase binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:170549
Molecular Function	GO:0005515	protein binding	IPI	J:210992
Molecular Function	GO:0005515	protein binding	IPI	J:114126
Molecular Function	GO:0005515	protein binding	IPI	J:225412
Molecular Function	GO:0005515	protein binding	IPI	J:245710
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0030159	signaling receptor complex adaptor activity	NAS	J:60559
Molecular Function	GO:0030159	signaling receptor complex adaptor activity	ISO	J:164563
Molecular Function	GO:0030159	signaling receptor complex adaptor activity	IBA	J:265628
Molecular Function	GO:0046332	SMAD binding	IPI	J:60559
Molecular Function	GO:0046332	SMAD binding	IBA	J:265628
Molecular Function	GO:0098919	structural constituent of postsynaptic density	ISO	J:155856
Molecular Function	GO:0098879	structural constituent of postsynaptic specialization	ISO	J:155856
Molecular Function	GO:0070699	type II activin receptor binding	IPI	J:108339
Molecular Function	GO:0070699	type II activin receptor binding	IBA	J:265628
Cellular Component	GO:0005923	bicellular tight junction	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005814	centriole	IDA	J:210992
Cellular Component	GO:0097546	ciliary base	IDA	J:210992
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:111059
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0030425	dendrite	IDA	J:161278
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0030425	dendrite	IBA	J:265628
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0098890	extrinsic component of postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0098982	GABA-ergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0005770	late endosome	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	IEA	J:60000
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0001917	photoreceptor inner segment	IDA	J:210992
Cellular Component	GO:0001750	photoreceptor outer segment	IDA	J:210992
Cellular Component	GO:0005886	plasma membrane	IDA	J:111059
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0036057	slit diaphragm	ISO	J:155856
Cellular Component	GO:0045202	synapse	ISO	J:155856
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	ISO	J:155856
Biological Process	GO:0072583	clathrin-dependent endocytosis	IMP	J:210992
Biological Process	GO:0006897	endocytosis	IEA	J:60000
Biological Process	GO:0032926	negative regulation of activin receptor signaling pathway	IDA	J:60559
Biological Process	GO:0030336	negative regulation of cell migration	ISO	J:155856
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	ISO	J:164563
Biological Process	GO:0038180	nerve growth factor signaling pathway	ISO	J:155856
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly	IDA	J:161278
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:155856
Biological Process	GO:0032516	positive regulation of phosphoprotein phosphatase activity	ISO	J:164563
Biological Process	GO:0002092	positive regulation of receptor internalization	ISO	J:164563
Biological Process	GO:2000809	positive regulation of synaptic vesicle clustering	IDA	J:161278
Biological Process	GO:0043113	receptor clustering	ISO	J:155856
Biological Process	GO:0043113	receptor clustering	IBA	J:265628
Biological Process	GO:0098696	regulation of neurotransmitter receptor localization to postsynaptic specialization membrane	ISO	J:155856
Biological Process	GO:0099179	regulation of synaptic membrane adhesion	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IBA	J:265628
Biological Process	GO:0007165	signal transduction	IPI	J:60559
Biological Process	GO:0060395	SMAD protein signal transduction	IDA	J:60559