GO Annotations Graph

• Symbol: Neu3
• Name: neuraminidase 3
• ID: MGI:1355305

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016997	alpha-sialidase activity	ISO	J:84529
Molecular Function	GO:0052794	exo-alpha-(2->3)-sialidase activity	IDA	J:297457
Molecular Function	GO:0052794	exo-alpha-(2->3)-sialidase activity	ISO	J:164563
Molecular Function	GO:0052794	exo-alpha-(2->3)-sialidase activity	IDA	J:89482
Molecular Function	GO:0052794	exo-alpha-(2->3)-sialidase activity	IDA	J:128021
Molecular Function	GO:0052795	exo-alpha-(2->6)-sialidase activity	IEA	J:72245
Molecular Function	GO:0052796	exo-alpha-(2->8)-sialidase activity	ISO	J:164563
Molecular Function	GO:0004308	exo-alpha-sialidase activity	ISO	J:164563
Molecular Function	GO:0004308	exo-alpha-sialidase activity	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0016798	hydrolase activity, acting on glycosyl bonds	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0031901	early endosome membrane	ISO	J:164563
Cellular Component	GO:0031901	early endosome membrane	IDA	J:128021
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:128021
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IBA	J:265628
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:89482
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:84529
Cellular Component	GO:0055038	recycling endosome membrane	ISO	J:164563
Cellular Component	GO:0055038	recycling endosome membrane	IDA	J:128021
Biological Process	GO:0005975	carbohydrate metabolic process	ISO	J:84529
Biological Process	GO:0006689	ganglioside catabolic process	IDA	J:297457
Biological Process	GO:0006689	ganglioside catabolic process	IDA	J:89482
Biological Process	GO:0006689	ganglioside catabolic process	ISO	J:164563
Biological Process	GO:0006689	ganglioside catabolic process	IDA	J:128021
Biological Process	GO:0006689	ganglioside catabolic process	IBA	J:265628
Biological Process	GO:0016042	lipid catabolic process	IEA	J:60000
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0008152	metabolic process	IEA	J:60000
Biological Process	GO:1900186	negative regulation of clathrin-dependent endocytosis	ISO	J:164563
Biological Process	GO:0009313	oligosaccharide catabolic process	ISO	J:164563
Biological Process	GO:0009313	oligosaccharide catabolic process	IBA	J:265628
Biological Process	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	ISO	J:164563