GO Annotations Graph

• Symbol: Slc7a8
• Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
• ID: MGI:1355323

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005275	amine transmembrane transporter activity	ISA	J:59975
Molecular Function	GO:0015171	amino acid transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015187	glycine transmembrane transporter activity	IMP	J:289067
Molecular Function	GO:0015180	L-alanine transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015179	L-amino acid transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0015179	L-amino acid transmembrane transporter activity	IDA	J:98013
Molecular Function	GO:0015190	L-leucine transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015175	neutral L-amino acid transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015175	neutral L-amino acid transmembrane transporter activity	IMP	J:289067
Molecular Function	GO:0015175	neutral L-amino acid transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0015101	organic cation transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015349	thyroid hormone transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015349	thyroid hormone transmembrane transporter activity	IMP	J:167825
Molecular Function	GO:0019534	toxin transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0022857	transmembrane transporter activity	IEA	J:72247
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:289067
Cellular Component	GO:0009925	basal plasma membrane	ISO	J:164563
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0031528	microvillus membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISA	J:59975
Biological Process	GO:0089718	amino acid import across plasma membrane	ISO	J:164563
Biological Process	GO:0003333	amino acid transmembrane transport	IBA	J:265628
Biological Process	GO:0006865	amino acid transport	ISO	J:164563
Biological Process	GO:0006865	amino acid transport	ISA	J:59975
Biological Process	GO:0015816	glycine transport	IMP	J:289067
Biological Process	GO:1904273	L-alanine import across plasma membrane	ISO	J:164563
Biological Process	GO:1902475	L-alpha-amino acid transmembrane transport	IDA	J:98013
Biological Process	GO:0015807	L-amino acid transport	IDA	J:98013
Biological Process	GO:1903801	L-leucine import across plasma membrane	ISO	J:164563
Biological Process	GO:0098713	leucine import across plasma membrane	ISO	J:164563
Biological Process	GO:0015820	leucine transport	IMP	J:289067
Biological Process	GO:0015804	neutral amino acid transport	IBA	J:265628
Biological Process	GO:0035524	proline transmembrane transport	IMP	J:289067
Biological Process	GO:0070327	thyroid hormone transport	ISO	J:164563
Biological Process	GO:0070327	thyroid hormone transport	IMP	J:167825
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0015827	tryptophan transport	IMP	J:289067
Biological Process	GO:0015829	valine transport	IMP	J:289067