GO Annotations Graph

• Symbol: Phgdh
• Name: 3-phosphoglycerate dehydrogenase
• ID: MGI:1355330

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051287	NAD binding	IEA	J:72247
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEA	J:72247
Molecular Function	GO:0004617	phosphoglycerate dehydrogenase activity	ISO	J:155856
Molecular Function	GO:0004617	phosphoglycerate dehydrogenase activity	IBA	J:265628
Molecular Function	GO:0004617	phosphoglycerate dehydrogenase activity	TAS	J:71630
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Biological Process	GO:0008652	amino acid biosynthetic process	IEA	J:60000
Biological Process	GO:0070314	G1 to G0 transition	IMP	J:145763
Biological Process	GO:0009448	gamma-aminobutyric acid metabolic process	IMP	J:145763
Biological Process	GO:0021782	glial cell development	IMP	J:145763
Biological Process	GO:0006541	glutamine metabolic process	IMP	J:145763
Biological Process	GO:0006544	glycine metabolic process	IMP	J:145763
Biological Process	GO:0006564	L-serine biosynthetic process	IEA	J:60000
Biological Process	GO:0006564	L-serine biosynthetic process	IEA	J:72247
Biological Process	GO:0006563	L-serine metabolic process	IMP	J:145763
Biological Process	GO:0021915	neural tube development	IMP	J:145763
Biological Process	GO:0022008	neurogenesis	IMP	J:145763
Biological Process	GO:0031175	neuron projection development	IMP	J:145763
Biological Process	GO:0010468	regulation of gene expression	IMP	J:145763
Biological Process	GO:0021510	spinal cord development	IMP	J:145763
Biological Process	GO:0019530	taurine metabolic process	IMP	J:145763
Biological Process	GO:0006566	threonine metabolic process	IMP	J:145763