GO Annotations Graph

• Symbol: Olig2
• Name: oligodendrocyte transcription factor 2
• ID: MGI:1355331

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IBA	J:265628
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISS	J:60687
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:86307
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:95698
Molecular Function	GO:0070888	E-box binding	IBA	J:265628
Molecular Function	GO:0071837	HMG box domain binding	IPI	J:175179
Molecular Function	GO:0042802	identical protein binding	IPI	J:95698
Molecular Function	GO:0005515	protein binding	IPI	J:120400
Molecular Function	GO:0005515	protein binding	IPI	J:112231
Molecular Function	GO:0005515	protein binding	IPI	J:86307
Molecular Function	GO:0005515	protein binding	IPI	J:95698
Molecular Function	GO:0046983	protein dimerization activity	IEA	J:72247
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:86307
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:86307
Cellular Component	GO:0005634	nucleus	IDA	J:157830
Cellular Component	GO:0005667	transcription regulator complex	ISS	J:60687
Biological Process	GO:0061564	axon development	IBA	J:265628
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0042552	myelination	IMP	J:105071
Biological Process	GO:0045665	negative regulation of neuron differentiation	IDA	J:71636
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:95698
Biological Process	GO:0007399	nervous system development	IDA	J:86307
Biological Process	GO:0030182	neuron differentiation	IDA	J:71636
Biological Process	GO:0048663	neuron fate commitment	IMP	J:75868
Biological Process	GO:0021778	oligodendrocyte cell fate specification	IEA	J:72247
Biological Process	GO:0048709	oligodendrocyte differentiation	ISO	J:155856
Biological Process	GO:0048709	oligodendrocyte differentiation	IMP	J:105071
Biological Process	GO:0048709	oligodendrocyte differentiation	IGI	J:71636
Biological Process	GO:0048714	positive regulation of oligodendrocyte differentiation	IGI	J:71636
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:86307
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISS	J:60687
Biological Process	GO:0007423	sensory organ development	IBA	J:265628
Biological Process	GO:0021522	spinal cord motor neuron differentiation	IMP	J:174745
Biological Process	GO:0021529	spinal cord oligodendrocyte cell differentiation	IGI	J:135661
Biological Process	GO:0021530	spinal cord oligodendrocyte cell fate specification	IDA	J:135661
Biological Process	GO:0021794	thalamus development	IMP	J:147427