GO Annotations Graph

• Symbol: Nckap1
• Name: NCK-associated protein 1
• ID: MGI:1355333

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:180006
Molecular Function	GO:0005515	protein binding	IPI	J:180006
Molecular Function	GO:0031267	small GTPase binding	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0031941	filamentous actin	IDA	J:241033
Cellular Component	GO:0030027	lamellipodium	IDA	J:241033
Cellular Component	GO:0030027	lamellipodium	IDA	J:88449
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0098794	postsynapse	IEP	J:201819
Cellular Component	GO:0098794	postsynapse	IDA	J:201819
Cellular Component	GO:0098794	postsynapse	IDA	J:201819
Cellular Component	GO:0098794	postsynapse	IDA	J:201819
Cellular Component	GO:0098794	postsynapse	IDA	J:201819
Cellular Component	GO:0001726	ruffle	IDA	J:241033
Cellular Component	GO:0031209	SCAR complex	ISO	J:164563
Cellular Component	GO:0031209	SCAR complex	IBA	J:265628
Biological Process	GO:0045176	apical protein localization	IDA	J:119028
Biological Process	GO:0045176	apical protein localization	IDA	J:119028
Biological Process	GO:0045176	apical protein localization	IDA	J:119028
Biological Process	GO:0045175	basal protein localization	IDA	J:119028
Biological Process	GO:0045175	basal protein localization	IDA	J:119028
Biological Process	GO:0045175	basal protein localization	IDA	J:119028
Biological Process	GO:0016477	cell migration	IBA	J:265628
Biological Process	GO:0042074	cell migration involved in gastrulation	IMP	J:119028
Biological Process	GO:0042074	cell migration involved in gastrulation	IMP	J:119028
Biological Process	GO:0000902	cell morphogenesis	IBA	J:265628
Biological Process	GO:0030031	cell projection assembly	IBA	J:265628
Biological Process	GO:0030866	cortical actin cytoskeleton organization	IBA	J:265628
Biological Process	GO:0010172	embryonic body morphogenesis	IMP	J:119028
Biological Process	GO:0048617	embryonic foregut morphogenesis	IMP	J:119028
Biological Process	GO:0035050	embryonic heart tube development	IMP	J:119028
Biological Process	GO:0007492	endoderm development	IMP	J:119028
Biological Process	GO:0030950	establishment or maintenance of actin cytoskeleton polarity	IMP	J:119028
Biological Process	GO:0001701	in utero embryonic development	IMP	J:119028
Biological Process	GO:0030032	lamellipodium assembly	IDA	J:88449
Biological Process	GO:0030032	lamellipodium assembly	IMP	J:119028
Biological Process	GO:0008078	mesodermal cell migration	IMP	J:119028
Biological Process	GO:0001843	neural tube closure	IMP	J:119028
Biological Process	GO:0048812	neuron projection morphogenesis	IBA	J:265628
Biological Process	GO:0030903	notochord development	IMP	J:119028
Biological Process	GO:0048570	notochord morphogenesis	IMP	J:119028
Biological Process	GO:0048339	paraxial mesoderm development	IMP	J:119028
Biological Process	GO:0048339	paraxial mesoderm development	IMP	J:119028
Biological Process	GO:0048340	paraxial mesoderm morphogenesis	IMP	J:119028
Biological Process	GO:0030838	positive regulation of actin filament polymerization	IDA	J:241033
Biological Process	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation	ISO	J:164563
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	ISO	J:164563
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	IDA	J:241033
Biological Process	GO:0050821	protein stabilization	IMP	J:119028
Biological Process	GO:0016601	Rac protein signal transduction	ISO	J:164563
Biological Process	GO:0032880	regulation of protein localization	IMP	J:119028
Biological Process	GO:0001756	somitogenesis	IMP	J:119028
Biological Process	GO:0007354	zygotic determination of anterior/posterior axis, embryo	IMP	J:119028
Biological Process	GO:0007354	zygotic determination of anterior/posterior axis, embryo	IMP	J:119028
Biological Process	GO:0007354	zygotic determination of anterior/posterior axis, embryo	IMP	J:119028
Biological Process	GO:0007354	zygotic determination of anterior/posterior axis, embryo	IMP	J:119028