GO Annotations Graph

• Symbol: Tslp
• Name: thymic stromal lymphopoietin
• ID: MGI:1855696

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005125	cytokine activity	ISO	J:164563
Molecular Function	GO:0005125	cytokine activity	IBA	J:265628
Molecular Function	GO:0005125	cytokine activity	IDA	J:64348
Molecular Function	GO:0005125	cytokine activity	IDA	J:64348
Molecular Function	GO:0005139	interleukin-7 receptor binding	ISO	J:164563
Molecular Function	GO:0005139	interleukin-7 receptor binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:245289
Cellular Component	GO:0005576	extracellular region	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	IDA	J:249547
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	ISO	J:164563
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	IBA	J:265628
Biological Process	GO:0050832	defense response to fungus	ISO	J:164563
Biological Process	GO:0050829	defense response to Gram-negative bacterium	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0071654	positive regulation of chemokine (C-C motif) ligand 1 production	ISO	J:164563
Biological Process	GO:0032722	positive regulation of chemokine production	ISO	J:164563
Biological Process	GO:0032722	positive regulation of chemokine production	IBA	J:265628
Biological Process	GO:0001961	positive regulation of cytokine-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0001961	positive regulation of cytokine-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0071657	positive regulation of granulocyte colony-stimulating factor production	ISO	J:164563
Biological Process	GO:0050729	positive regulation of inflammatory response	ISO	J:164563
Biological Process	GO:0050729	positive regulation of inflammatory response	IBA	J:265628
Biological Process	GO:0032733	positive regulation of interleukin-10 production	ISO	J:164563
Biological Process	GO:0032733	positive regulation of interleukin-10 production	IBA	J:265628
Biological Process	GO:0032736	positive regulation of interleukin-13 production	ISO	J:164563
Biological Process	GO:0032736	positive regulation of interleukin-13 production	IBA	J:265628
Biological Process	GO:0032754	positive regulation of interleukin-5 production	ISO	J:164563
Biological Process	GO:0032754	positive regulation of interleukin-5 production	IBA	J:265628
Biological Process	GO:0032755	positive regulation of interleukin-6 production	ISO	J:164563
Biological Process	GO:0032755	positive regulation of interleukin-6 production	IBA	J:265628
Biological Process	GO:0033005	positive regulation of mast cell activation	ISO	J:164563
Biological Process	GO:1904894	positive regulation of receptor signaling pathway via STAT	ISO	J:164563
Biological Process	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	ISO	J:164563
Biological Process	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	IBA	J:265628
Biological Process	GO:0007165	signal transduction	IDA	J:64348