GO Annotations Graph

• Symbol: Usp2
• Name: ubiquitin specific peptidase 2
• ID: MGI:1858178

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030332	cyclin binding	ISO	J:164563
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	ISO	J:164563
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	ISO	J:155856
Molecular Function	GO:0008234	cysteine-type peptidase activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	IDA	J:108694
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008233	peptidase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:243462
Molecular Function	GO:0005515	protein binding	IPI	J:243462
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0005813	centrosome	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:243462
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:108694
Cellular Component	GO:0016020	membrane	IDA	J:243462
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0048512	circadian behavior	IMP	J:215857
Biological Process	GO:0032922	circadian regulation of gene expression	IMP	J:243462
Biological Process	GO:0032922	circadian regulation of gene expression	IMP	J:215857
Biological Process	GO:0043153	entrainment of circadian clock by photoperiod	IMP	J:215857
Biological Process	GO:0045475	locomotor rhythm	IMP	J:215857
Biological Process	GO:0007517	muscle organ development	IEA	J:60000
Biological Process	GO:0051926	negative regulation of calcium ion transport	IMP	J:243462
Biological Process	GO:0048642	negative regulation of skeletal muscle tissue development	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045931	positive regulation of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0048643	positive regulation of skeletal muscle tissue development	ISO	J:155856
Biological Process	GO:0016579	protein deubiquitination	IMP	J:215857
Biological Process	GO:0016579	protein deubiquitination	ISO	J:155856
Biological Process	GO:0016579	protein deubiquitination	ISO	J:164563
Biological Process	GO:0050821	protein stabilization	ISO	J:164563
Biological Process	GO:0006508	proteolysis	IEA	J:60000
Biological Process	GO:0048511	rhythmic process	IEA	J:60000
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	IEA	J:72247