GO Annotations Graph

• Symbol: Hnrnpu
• Name: heterogeneous nuclear ribonucleoprotein U
• ID: MGI:1858195

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	ISO	J:164563
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0031490	chromatin DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0003725	double-stranded RNA binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0106222	lncRNA binding	IDA	J:272999
Molecular Function	GO:0003730	mRNA 3'-UTR binding	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0008143	poly(A) binding	ISO	J:164563
Molecular Function	GO:0017130	poly(C) RNA binding	ISO	J:164563
Molecular Function	GO:0017130	poly(C) RNA binding	IBA	J:265628
Molecular Function	GO:0034046	poly(G) binding	ISO	J:155856
Molecular Function	GO:0034046	poly(G) binding	ISO	J:164563
Molecular Function	GO:0034046	poly(G) binding	IBA	J:265628
Molecular Function	GO:0036002	pre-mRNA binding	ISO	J:164563
Molecular Function	GO:0036002	pre-mRNA binding	IBA	J:265628
Molecular Function	GO:1990841	promoter-specific chromatin binding	ISO	J:155856
Molecular Function	GO:1990841	promoter-specific chromatin binding	IDA	J:243396
Molecular Function	GO:1990841	promoter-specific chromatin binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:173042
Molecular Function	GO:0005515	protein binding	IPI	J:204641
Molecular Function	GO:0005515	protein binding	IPI	J:244072
Molecular Function	GO:0005515	protein binding	IPI	J:137945
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0043021	ribonucleoprotein complex binding	ISO	J:164563
Molecular Function	GO:0043021	ribonucleoprotein complex binding	ISO	J:155856
Molecular Function	GO:0043021	ribonucleoprotein complex binding	IBA	J:265628
Molecular Function	GO:0003723	RNA binding	IDA	J:164278
Molecular Function	GO:0003723	RNA binding	ISO	J:155856
Molecular Function	GO:0003723	RNA binding	ISO	J:164563
Molecular Function	GO:0003723	RNA binding	IDA	J:244072
Molecular Function	GO:0003723	RNA binding	IDA	J:243474
Molecular Function	GO:0003723	RNA binding	IPI	J:272999
Molecular Function	GO:0099122	RNA polymerase II C-terminal domain binding	IDA	J:243396
Molecular Function	GO:0099122	RNA polymerase II C-terminal domain binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:136001
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000993	RNA polymerase II complex binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:243396
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0003697	single-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0003727	single-stranded RNA binding	ISO	J:164563
Molecular Function	GO:0017069	snRNA binding	ISO	J:164563
Molecular Function	GO:0017069	snRNA binding	IBA	J:265628
Molecular Function	GO:0070034	telomerase RNA binding	ISO	J:164563
Molecular Function	GO:0001097	TFIIH-class transcription factor complex binding	ISO	J:164563
Molecular Function	GO:0001097	TFIIH-class transcription factor complex binding	IBA	J:265628
Molecular Function	GO:0003714	transcription corepressor activity	ISO	J:164563
Molecular Function	GO:0003714	transcription corepressor activity	IBA	J:265628
Cellular Component	GO:0071013	catalytic step 2 spliceosome	ISO	J:164563
Cellular Component	GO:0071013	catalytic step 2 spliceosome	IBA	J:265628
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005813	centrosome	IBA	J:265628
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000775	chromosome, centromeric region	IEA	J:60000
Cellular Component	GO:0070937	CRD-mediated mRNA stability complex	ISO	J:164563
Cellular Component	GO:0070937	CRD-mediated mRNA stability complex	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	ISO	J:164563
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0030425	dendrite	IDA	J:96571
Cellular Component	GO:0032839	dendrite cytoplasm	IDA	J:96571
Cellular Component	GO:0098577	inactive sex chromosome	IDA	J:164278
Cellular Component	GO:0098577	inactive sex chromosome	ISO	J:164563
Cellular Component	GO:0098577	inactive sex chromosome	IBA	J:265628
Cellular Component	GO:0000776	kinetochore	ISO	J:164563
Cellular Component	GO:0000776	kinetochore	IBA	J:265628
Cellular Component	GO:0030496	midbody	ISO	J:164563
Cellular Component	GO:0072686	mitotic spindle	ISO	J:164563
Cellular Component	GO:1990498	mitotic spindle microtubule	ISO	J:164563
Cellular Component	GO:1990498	mitotic spindle microtubule	IBA	J:265628
Cellular Component	GO:1990023	mitotic spindle midzone	ISO	J:164563
Cellular Component	GO:1990023	mitotic spindle midzone	IBA	J:265628
Cellular Component	GO:0000228	nuclear chromosome	ISO	J:164563
Cellular Component	GO:0000228	nuclear chromosome	IBA	J:265628
Cellular Component	GO:0016363	nuclear matrix	ISO	J:164563
Cellular Component	GO:0016363	nuclear matrix	IBA	J:265628
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0016607	nuclear speck	IBA	J:265628
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:136001
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:204641
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:1990904	ribonucleoprotein complex	ISO	J:155856
Cellular Component	GO:1990904	ribonucleoprotein complex	ISO	J:164563
Cellular Component	GO:1990904	ribonucleoprotein complex	IDA	J:272999
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ISO	J:164563
Cellular Component	GO:0005681	spliceosomal complex	IEA	J:60000
Cellular Component	GO:0005697	telomerase holoenzyme complex	ISO	J:164563
Cellular Component	GO:0005697	telomerase holoenzyme complex	IBA	J:265628
Biological Process	GO:1990845	adaptive thermogenesis	IMP	J:244072
Biological Process	GO:0055013	cardiac muscle cell development	IMP	J:223139
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	ISO	J:155856
Biological Process	GO:0071385	cellular response to glucocorticoid stimulus	ISO	J:164563
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IDA	J:243396
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0032922	circadian regulation of gene expression	IDA	J:136001
Biological Process	GO:0070934	CRD-mediated mRNA stabilization	ISO	J:164563
Biological Process	GO:0070934	CRD-mediated mRNA stabilization	IBA	J:265628
Biological Process	GO:0098963	dendritic transport of messenger ribonucleoprotein complex	IDA	J:96571
Biological Process	GO:0098963	dendritic transport of messenger ribonucleoprotein complex	IDA	J:96571
Biological Process	GO:0098963	dendritic transport of messenger ribonucleoprotein complex	IMP	J:96571
Biological Process	GO:0098963	dendritic transport of messenger ribonucleoprotein complex	IDA	J:96571
Biological Process	GO:0009048	dosage compensation by inactivation of X chromosome	IMP	J:164278
Biological Process	GO:0051457	maintenance of protein location in nucleus	ISO	J:164563
Biological Process	GO:0016071	mRNA metabolic process	IMP	J:272999
Biological Process	GO:0006397	mRNA processing	IEA	J:60000
Biological Process	GO:0048255	mRNA stabilization	ISO	J:164563
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0033673	negative regulation of kinase activity	ISO	J:164563
Biological Process	GO:1900152	negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	ISO	J:164563
Biological Process	GO:2000737	negative regulation of stem cell differentiation	IMP	J:243396
Biological Process	GO:2000737	negative regulation of stem cell differentiation	ISO	J:164563
Biological Process	GO:0032211	negative regulation of telomere maintenance via telomerase	ISO	J:164563
Biological Process	GO:0032211	negative regulation of telomere maintenance via telomerase	IBA	J:265628
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0034244	negative regulation of transcription elongation by RNA polymerase II	ISO	J:164563
Biological Process	GO:1902425	positive regulation of attachment of mitotic spindle microtubules to kinetochore	ISO	J:164563
Biological Process	GO:1902425	positive regulation of attachment of mitotic spindle microtubules to kinetochore	IBA	J:265628
Biological Process	GO:0090336	positive regulation of brown fat cell differentiation	IMP	J:244072
Biological Process	GO:2000767	positive regulation of cytoplasmic translation	ISO	J:164563
Biological Process	GO:2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity	ISO	J:155856
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:155856
Biological Process	GO:2000648	positive regulation of stem cell proliferation	IMP	J:164278
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:204641
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:243396
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:1902889	protein localization to spindle microtubule	ISO	J:164563
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	ISO	J:164563
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	IBA	J:265628
Biological Process	GO:1902275	regulation of chromatin organization	ISO	J:164563
Biological Process	GO:1902275	regulation of chromatin organization	IBA	J:265628
Biological Process	GO:0007346	regulation of mitotic cell cycle	ISO	J:164563
Biological Process	GO:1901673	regulation of mitotic spindle assembly	ISO	J:164563
Biological Process	GO:1901673	regulation of mitotic spindle assembly	IBA	J:265628
Biological Process	GO:0048511	rhythmic process	IEA	J:60000
Biological Process	GO:1990280	RNA localization to chromatin	IMP	J:164278
Biological Process	GO:1990280	RNA localization to chromatin	IBA	J:265628
Biological Process	GO:0008380	RNA splicing	IEA	J:60000