GO Annotations Graph

• Symbol: Slc5a3
• Name: solute carrier family 5 (inositol transporters), member 3
• ID: MGI:1858226

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005412	glucose:sodium symporter activity	IBA	J:265628
Molecular Function	GO:0005367	myo-inositol:sodium symporter activity	ISO	J:164563
Molecular Function	GO:0015459	potassium channel regulator activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:258659
Molecular Function	GO:0005515	protein binding	IPI	J:258659
Molecular Function	GO:0015293	symporter activity	IEA	J:60000
Molecular Function	GO:0022857	transmembrane transporter activity	IEA	J:72247
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:258659
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:258659
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0008076	voltage-gated potassium channel complex	IDA	J:258659
Biological Process	GO:0006020	inositol metabolic process	IBA	J:265628
Biological Process	GO:0006020	inositol metabolic process	IMP	J:140213
Biological Process	GO:0006020	inositol metabolic process	IMP	J:111651
Biological Process	GO:0006020	inositol metabolic process	IMP	J:140213
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0015798	myo-inositol transport	IBA	J:265628
Biological Process	GO:0015798	myo-inositol transport	IMP	J:83591
Biological Process	GO:0015798	myo-inositol transport	IMP	J:102665
Biological Process	GO:0007422	peripheral nervous system development	IMP	J:102665
Biological Process	GO:0043085	positive regulation of catalytic activity	IMP	J:287054
Biological Process	GO:1905477	positive regulation of protein localization to membrane	IMP	J:287054
Biological Process	GO:1903428	positive regulation of reactive oxygen species biosynthetic process	IMP	J:287054
Biological Process	GO:0043576	regulation of respiratory gaseous exchange	IMP	J:83591
Biological Process	GO:0032409	regulation of transporter activity	IDA	J:258659
Biological Process	GO:0006814	sodium ion transport	IEA	J:60000
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247